Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8434452 | 0.80 | MMP8 (0.52) | MMP8PIN1ALDH1A1RECQLHPGD | |
| SCHEMBL19461337 | 0.77 | KDM4E (0.49) | MMP8ALDH1A1GAAPOLBNPSR1 | |
| SCHEMBL12501769 | 0.75 | PKM (0.50) | ALDH1A1TSHRCYP4F2CYP4A11SMN1; SMN2 | |
| SCHEMBL8710582 | 0.74 | MMP8 (0.79) | MMP8PIN1ALDH1A1RECQLTSHR | |
| SCHEMBL10981821 | 0.73 | CYP4F2 (0.65) | ALDH1A1CYP4F2CYP4A11SMN1; SMN2MAPT | |
| SCHEMBL8677565 | 0.72 | GAA (0.39) | ALDH1A1TSHRSMN1; SMN2MAPTTP53 | |
| SCHEMBL10061749 | 0.71 | RIPK1 (0.44) | ALDH1A1TSHRSMN1; SMN2MAPTTP53 | |
| SCHEMBL19491465 | 0.70 | KDM4E (0.49) | MMP8ALDH1A1RECQLGAANPSR1 | |
| SCHEMBL8706224 | 0.70 | PKM (0.63) | MMP8ALDH1A1RECQLHPGDTSHR | |
| SCHEMBL28008239 | 0.70 | MMP8 (0.48) | MMP8PIN1ALDH1A1RECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962269-A | ANALGESICS | ELI LILLY AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |