Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.52 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12802659 | 0.89 | RIPK1 (0.49) | MMP8PIN1RIPK1ALDH1A1RECQL | |
| SCHEMBL29277103 | 0.87 | PIN1 (0.47) | MMP8PIN1RIPK1ALDH1A1RECQL | |
| SCHEMBL28017217 | 0.84 | PIN1 (0.45) | MMP8PIN1RIPK1ALDH1A1RECQL | |
| SCHEMBL19461337 | 0.80 | KDM4E (0.49) | MMP8ALDH1A1EPHX2POLBKMT2A | |
| SCHEMBL11865914 | 0.80 | MMP8 (0.49) | MMP8PIN1ALDH1A1RECQLTSHR | |
| SCHEMBL9849152 | 0.80 | ALDH1A1 (0.67) | MMP8PIN1RIPK1ALDH1A1RECQL | |
| SCHEMBL15840430 | 0.80 | MMP8 (0.40) | MMP8PIN1ALDH1A1TSHRMAPT | |
| SCHEMBL16393647 | 0.80 | RIPK1 (0.47) | MMP8RIPK1ALDH1A1KMT2APPARA | |
| SCHEMBL12713184 | 0.79 | TSHR (0.48) | MMP8ALDH1A1RECQLTSHRMAPT | |
| SCHEMBL8710582 | 0.78 | MMP8 (0.79) | MMP8PIN1ALDH1A1RECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11248067-B2 | Hybrid supported metallocene catalyst, and polyolefin resin having excellent processability and using same | HANWHA CHEMICAL CORPORATION (KR) | 2022-02-15 | — | — | US | disclosed |
| US-20190263942-A1 | HYBRID SUPPORTED METALLOCENE CATALYST, AND POLYOLEFIN RESIN HAVING EXCELLENT PROCESSABILITY AND USING SAME | HANWHA CHEMICAL CORPORATION (KR) | 2019-08-29 | — | — | US | disclosed |
| WO-2017188602-A1 | HYBRID SUPPORTED METALLOCENE CATALYST, AND POLYOLEFIN RESIN HAVING EXCELLENT PROCESSABILITY AND USING SAME | 한화케미칼 주식회사 | 2017-11-02 | — | — | WO | disclosed |
| US-9193669-B2 | Compounds for treating ophthalmic diseases and disorders | ACUCELA INC. (US) | 2015-11-24 | — | — | US | disclosed |
| US-5942459-A | ALUMOXANE-FREE MIXTURE OF TRANSITION METAL METALLOCENE, ORGANOALUMINUM COMPOUND, BORIC ACID-CONTAINING POWDER | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0728773-B1 | Catalysts for olefin polymerization and a process for preparing olefin polymers therewith | MITSUBISHI CHEM CORP (JP) | 1998-11-04 | — | — | EP | disclosed |
| EP-0728773-A1 | Catalysts for olefin polymerization and a process for preparing olefin polymers therewith | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-08-28 | — | — | EP | disclosed |