Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.54 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | HRH1 | P35367 | 3/20 | 0.43 |
| ▸ | MC4R | P32245 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11865232 | 0.90 | SIGMAR1 (0.53) | SIGMAR1DRD2HRH1SLC6A4SLC6A3 | |
| SCHEMBL11748974 | 0.89 | SIGMAR1 (0.54) | SIGMAR1DRD2HRH1SLC6A4SLC6A3 | |
| SCHEMBL11863524 | 0.87 | SIGMAR1 (0.58) | SIGMAR1KDM1AHRH3 | |
| SCHEMBL11750620 | 0.83 | HRH3 (0.49) | SIGMAR1DRD2CHRM1CHRM3DRD3 | |
| SCHEMBL11750577 | 0.76 | HTR2A (0.36) | DRD2HTR2ASLC6A2HTR2CSLC6A4 | |
| SCHEMBL11862034 | 0.75 | SIGMAR1 (0.47) | SIGMAR1KDM1ACYP1A2CYP2D6DRD2 | |
| SCHEMBL11868967 | 0.75 | TSHR (0.55) | DRD2HRH1HTR1AHTR2ALMNA | |
| Hydrochloric Acid SCHEMBL11862820 | 0.74 | SIGMAR1 (0.46) | SIGMAR1CYP1A2CYP2D6DRD2HTR1A | |
| SCHEMBL26382814 | 0.74 | HRH1 (0.73) | SIGMAR1DRD2HRH1HTR1AHTR2A | |
| SCHEMBL11866467 | 0.73 | KCNH2 (0.44) | SIGMAR1DRD2HTR1AHTR2AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |