Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11863524 | 0.86 | SIGMAR1 (0.58) | HRH3SPHK1SIGMAR1 | |
| SCHEMBL11868978 | 0.83 | SIGMAR1 (0.54) | HRH3KCNH2SIGMAR1CCR3CHRM2 | |
| SCHEMBL11865232 | 0.81 | SIGMAR1 (0.53) | HRH3SIGMAR1DRD2 | |
| SCHEMBL11748974 | 0.80 | SIGMAR1 (0.54) | HRH3SIGMAR1DRD2 | |
| SCHEMBL11750613 | 0.79 | ACHE (0.51) | HRH3KCNH2CHRM2CHRM4CHRM5 | |
| SCHEMBL11679286 | 0.72 | SIGMAR1 (0.62) | HRH3SPHK1SIGMAR1 | |
| SCHEMBL11867678 | 0.70 | KCNH2 (0.40) | KCNH2SIGMAR1DRD2DRD4DRD3 | |
| SCHEMBL11677886 | 0.70 | SIGMAR1 (0.70) | HRH3KCNH2SIGMAR1CCR3ABCB1 | |
| SCHEMBL7733753 | 0.69 | GNAO1 (0.70) | HRH3KCNH2CHRM2CHRM4CHRM5 | |
| SCHEMBL11750577 | 0.69 | HTR2A (0.36) | DRD2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |