Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 3/20 | 0.37 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 5/20 | 0.34 |
| ▸ | ARNT | P27540 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11867053 | 0.88 | EPAS1 (0.38) | EPAS1VEGFAHPGDLMNASMN1; SMN2 | |
| SCHEMBL11863601 | 0.85 | DCTPP1 (0.36) | EPAS1VEGFAHPGDLMNASMN1; SMN2 | |
| SCHEMBL11810808 | 0.85 | LMNA (0.39) | EPAS1HPGDLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11857450 | 0.85 | ALDH1A1 (0.34) | EPAS1VEGFAHPGDLMNASMN1; SMN2 | |
| SCHEMBL11867059 | 0.85 | KMT2A (0.40) | LMNACYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL11869897 | 0.84 | ALDH1A1 (0.38) | CYP3A4CYP2C19CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL11858559 | 0.83 | ABL1 (0.36) | EPAS1VEGFAHPGDLMNASMN1; SMN2 | |
| SCHEMBL11857528 | 0.83 | ALDH1A1 (0.38) | CYP3A4CYP2C19CYP1A2CYP2D6ALDH1A1 | |
| SCHEMBL11857518 | 0.82 | EPAS1 (0.33) | EPAS1VEGFAHPGDLMNASMN1; SMN2 | |
| SCHEMBL11867426 | 0.81 | EPAS1 (0.32) | EPAS1VEGFAHPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954788-A | INTERMEDIATES FOR HERBIDIDES | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |