Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.39 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11869804 | 0.86 | POLB (0.59) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL31037935 | 0.76 | POLB (0.62) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL28569270 | 0.76 | POLB (0.62) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL9075843 | 0.75 | MAOB (0.71) | PTPN1ALDH1A1MAOBCYP19A1 | |
| SCHEMBL11872015 | 0.73 | PTPN1 (1.00) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL21591455 | 0.73 | PON1 (0.55) | POLBKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL29950744 | 0.73 | PTPN1 (1.00) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL17383983 | 0.72 | KMT2A (0.60) | KMT2AALDH1A1MAPTHPGDMCL1 | |
| SCHEMBL11549451 | 0.72 | POLB (0.57) | POLBKMT2AMEN1PTPN1ALDH1A1 | |
| SCHEMBL11510369 | 0.72 | MAOB (0.59) | POLBKMT2AMEN1PTPN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807264-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2021-04-21 | — | — | EP | disclosed |
| WO-2019238786-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2019-12-19 | — | — | WO | disclosed |