Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806075 | 0.80 | MTNR1A (0.60) | MTNR1AMTNR1BALDH1A1MAPTLMNA | |
| SCHEMBL7419329 | 0.80 | MTNR1A (0.56) | MTNR1AMTNR1BALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11869476 | 0.80 | KMT2A (0.52) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL11867992 | 0.79 | NOTUM (0.56) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL7417947 | 0.79 | MTNR1A (0.55) | MTNR1AMTNR1BCTSDALDH1A1MAPT | |
| SCHEMBL15562974 | 0.78 | MAPT (0.55) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL11864053 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL15562971 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDSMN1; SMN2NPC1 | |
| SCHEMBL15562863 | 0.76 | POLB (0.58) | ALDH1A1MAPTLMNAHPGDSMN1; SMN2 | |
| SCHEMBL11868155 | 0.76 | ALDH1A1 (0.52) | ALDH1A1MAPTHPGDSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | claimed |
| EP-2882430-A1 | ANTIBACTERIAL INHIBITORS | McMaster University (CA) | 2015-06-17 | — | — | EP | claimed |
| WO-2014022923-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2014-02-13 | — | — | WO | claimed |
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2015-08-27 | — | — | US | disclosed |
| EP-2882430-A1 | ANTIBACTERIAL INHIBITORS | McMaster University (CA) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014022923-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2014-02-13 | — | — | WO | disclosed |
| WO-2014022923-A1 | ANTIBACTERIAL INHIBITORS | MCMASTER UNIVERSITY (CA) | 2014-02-13 | — | — | WO | disclosed |
| US-3972905-A | FUNGICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150237857-A1 | ANTIBACTERIAL INHIBITORS | MRPL21, Q6ZSR9, SPOUT1 | MTNR1A 4487/4885MTNR1B 4499/4885CTSD 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.