Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878658 | 1.00 | MEN1 (0.47) | MEN1KMT2AHPGDNPSR1ACHE | |
| SCHEMBL216973 | 0.78 | ACHE (0.56) | MEN1KMT2AHPGDNPSR1ACHE | |
| SCHEMBL11873269 | 0.77 | LMNA (0.47) | HPGDNPSR1ACHEALDH1A1CHRM2 | |
| SCHEMBL11873278 | 0.77 | LMNA (0.47) | HPGDNPSR1ACHEALDH1A1CHRM2 | |
| SCHEMBL7945985 | 0.74 | KMT2A (0.61) | MEN1KMT2AHPGDNPSR1ALDH1A1 | |
| SCHEMBL6270102 | 0.74 | MEN1 (0.61) | MEN1KMT2AHPGDALDH1A1DRD2 | |
| SCHEMBL11756868 | 0.73 | ALDH1A1 (0.42) | HPGDNPSR1ACHEALDH1A1CHRM2 | |
| SCHEMBL12609505 | 0.73 | HPGD (0.67) | MEN1KMT2AHPGDNPSR1ALDH1A1 | |
| SCHEMBL11756862 | 0.72 | ALDH1A1 (0.56) | KMT2AHPGDNPSR1ACHEALDH1A1 | |
| SCHEMBL11756855 | 0.72 | ALDH1A1 (0.56) | KMT2AHPGDNPSR1ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985895-A | DIURETIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-10-12 | — | — | US | disclosed |