SCHEMBL28050408

SCHEMBL28050408

O=C=NC1(N=C=O)C=Cc2cccc3cccc1c23.[H+]

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TXNRD1 Q16881 1/20 0.31
TXNRD3 Q86VQ6 1/20 0.31
TXNRD2 Q9NNW7 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL626688 0.98 TXNRD1 (0.31) TXNRD1TXNRD3TXNRD2MEN1MAPT
SCHEMBL27644016 0.82
Toluene Diisocyanate SCHEMBL28119834 0.79 CYP3A4 (0.52)
SCHEMBL8216368 0.78
SCHEMBL11841672 0.75
SCHEMBL28193284 0.74 GABRA1 (0.37)
SCHEMBL11874656 0.71 TYMS (0.33) TXNRD1TXNRD3TXNRD2MEN1MAPT
SCHEMBL28817812 0.68 ALDH1A1 (0.33) MEN1MAPTMAPK1KMT2A
SCHEMBL9700157 0.68 RAD52 (0.35) MEN1MAPTMAPK1KMT2A
SCHEMBL8984508 0.68 ALDH1A1 (0.33) TXNRD1TXNRD3TXNRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104321308-B The manufacture method of new poly-thiol compound and comprise this polymerizable composition for optical material KOC SOLUTION CO.,LTD. (KR) 2016-06-01 CN disclosed