Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5038274 | 0.73 | GLA (0.45) | KDM4ETSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3184231 | 0.65 | PDE4B (0.44) | KDM4ETP53TSHRALDH1A1HTT | |
| SCHEMBL10272811 | 0.65 | ALDH1A1 (0.42) | KDM4ESIGMAR1MAPK13MAPK12MAPK11 | |
| SCHEMBL12123785 | 0.62 | ALDH1A1 (0.70) | KDM4ETP53TSHRALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL7929072 | 0.62 | ALDH1A1 (0.70) | KDM4ETP53TSHRALDH1A1HTT | |
| SCHEMBL1138033 | 0.61 | PDE4B (0.53) | SIGMAR1ALDH1A1HTTSMN1; SMN2MAPK1 | |
| SCHEMBL4959749 | 0.60 | SMN1; SMN2 (0.40) | KDM4ESIGMAR1MAPK13MAPK12MAPK11 | |
| Oxalic Acid SCHEMBL1355903 | 0.59 | SIGMAR1 (0.67) | KDM4ETP53TSHRSIGMAR1ALDH1A1 | |
| SCHEMBL18127455 | 0.59 | ALDH1A1 (0.37) | KDM4EALDH1A1SMN1; SMN2GAA | |
| SCHEMBL21749204 | 0.59 | HRH3 (0.76) | KDM4ETP53TSHRALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888356-B2 | Antibiotics containing borinic acid complexes and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2011-02-15 | — | — | US | claimed |