Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10272811 | 0.79 | ALDH1A1 (0.42) | ALDH1A1HSD17B10KDM4ESMN1; SMN2LMNA | |
| SCHEMBL28120475 | 0.77 | ESR1 (0.41) | SMN1; SMN2LMNACYP2C19 | |
| SCHEMBL17669581 | 0.73 | FPR2 (0.52) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4959749 | 0.73 | SMN1; SMN2 (0.40) | ALDH1A1KDM5AKDM5BHSD17B10KDM4E | |
| SCHEMBL29651715 | 0.73 | ARG1 (0.42) | ALDH1A1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL1187499 | 0.73 | KDM4E (0.46) | ALDH1A1KDM4ESMN1; SMN2LMNATSHR | |
| SCHEMBL18127455 | 0.72 | ALDH1A1 (0.37) | ALDH1A1KMT2AKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL14553277 | 0.72 | ALDH1A1 (0.51) | ALDH1A1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL13166801 | 0.72 | TSHR (0.41) | ALDH1A1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8983983 | 0.72 | MAPK13 (0.39) | ALDH1A1HSD17B10SMN1; SMN2LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1980564-A1 | Antibiotics containing borinic acid complexes and methods of use | Anacor Pharmaceuticals, Inc. (US) | 2008-10-15 | — | — | EP | disclosed |