Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | PRCP | P42785 | 5/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11879132 | 0.96 | OPRD1 (0.46) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11880458 | 0.89 | OPRD1 (0.53) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11857141 | 0.84 | SIGMAR1 (0.50) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11878975 | 0.84 | PRCP (0.39) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11881722 | 0.83 | OPRD1 (0.51) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11682595 | 0.83 | OPRD1 (0.45) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11883504 | 0.82 | OPRD1 (0.49) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11879294 | 0.81 | OPRD1 (0.56) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11852685 | 0.80 | PRCP (0.47) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11853705 | 0.78 | SIGMAR1 (0.49) | OPRD1KCNH2PRCPSIGMAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3980787-A | DIURETIC AND ANTIHYPERTENSIVE AGENTS | AMERICAN HOECHST CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |