Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PRCP | P42785 | 6/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11857141 | 0.89 | SIGMAR1 (0.50) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11680301 | 0.86 | OPRD1 (0.43) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11684960 | 0.86 | OPRD1 (0.57) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11687660 | 0.84 | PRCP (0.49) | OPRD1KCNH2PRCPSIGMAR1 | |
| SCHEMBL11880970 | 0.83 | OPRD1 (0.44) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11853705 | 0.82 | SIGMAR1 (0.49) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11852685 | 0.82 | PRCP (0.47) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11686121 | 0.82 | TSHR (0.42) | OPRD1KCNH2PRCPSIGMAR1ADRA2A | |
| SCHEMBL11684464 | 0.81 | PRCP (0.39) | PRCP | |
| SCHEMBL11879132 | 0.81 | OPRD1 (0.46) | OPRD1KCNH2PRCPSIGMAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024263-A | ANALGESIC, ANTICONVULSANT, ANTIDEPRESSANT | AMERICAN HOECHST CORPORATION (US) | 1977-05-17 | — | — | US | claimed |
| US-4024263-A | ANALGESIC, ANTICONVULSANT, ANTIDEPRESSANT | AMERICAN HOECHST CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |