Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 12/20 | 0.50 |
| ▸ | CCKAR | P32238 | 8/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544285 | 0.80 | CCKBR (0.43) | CCKBRCCKARRIPK1MEN1ALDH1A1 | |
| SCHEMBL7544295 | 0.80 | CCKBR (0.43) | CCKBRCCKARRIPK1MEN1ALDH1A1 | |
| SCHEMBL8592722 | 0.77 | CCKBR (0.49) | CCKBRCCKARRIPK1ALDH1A1KDM4E | |
| SCHEMBL7546577 | 0.71 | CCKBR (0.52) | CCKBRCCKAR | |
| SCHEMBL2364518 | 0.70 | GABRA1 (0.54) | CCKBRCCKARMEN1KMT2A | |
| SCHEMBL6159010 | 0.68 | MEN1 (0.45) | CCKBRCCKARMEN1ALDH1A1KMT2A | |
| SCHEMBL6157468 | 0.68 | MEN1 (0.45) | CCKBRCCKARMEN1ALDH1A1KMT2A | |
| SCHEMBL7552264 | 0.68 | MEN1 (0.41) | CCKBRCCKARMEN1ALDH1A1KMT2A | |
| SCHEMBL7552256 | 0.68 | MEN1 (0.41) | CCKBRCCKARMEN1ALDH1A1KMT2A | |
| SCHEMBL9527176 | 0.67 | CCKBR (1.00) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3915961-A | 5-Aryl-1H-1,4-benzodiazepine-2(3H)-one-3-phosphonic acids, derivatives and processes for their use | AMERICAN HOME PROD | 1975-10-28 | — | — | US | disclosed |
| US-3915961-A | 5-Aryl-1H-1,4-benzodiazepine-2(3H)-one-3-phosphonic acids, derivatives and processes for their use | AMERICAN HOME PROD | 1975-10-28 | — | — | US | disclosed |