Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21587364 | 0.80 | IMPDH2 (0.39) | IMPDH2 | |
| SCHEMBL5823918 | 0.80 | BACE1 (0.36) | IMPDH2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL30660353 | 0.76 | ALDH1A1 (0.38) | IMPDH2GABRA1GABRB2 | |
| SCHEMBL10399629 | 0.71 | GABRP (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5823143 | 0.71 | TLR8 (0.36) | IMPDH2GABRA1GABRB2NOS2NOS3 | |
| SCHEMBL248606 | 0.69 | IMPDH2 (0.37) | IMPDH2NOS2NOS3NOS1BACE1 | |
| SCHEMBL6535908 | 0.68 | TLR8 (0.48) | NOS2BACE1NCF1 | |
| SCHEMBL845635 | 0.67 | IMPDH2 (0.53) | IMPDH2GABRA1GABRB2 | |
| SCHEMBL21587310 | 0.67 | IMPDH2 (0.32) | IMPDH2 | |
| SCHEMBL5824067 | 0.67 | BACE1 (0.42) | IMPDH2GABRA1GABRB2NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3717579-A | BIOCIDAL PREPARATION | GOLDSCHMIDT AG TH | 1973-02-20 | — | — | US | disclosed |