Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13921299 | 0.76 | MAPK1 (0.82) | MAPK1SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL9039655 | 0.74 | MAPK1 (0.72) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9631976 | 0.72 | MAPK1 (0.73) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11521605 | 0.70 | MAPK1 (0.79) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10409949 | 0.70 | MAPK1 (0.79) | MAPK1SMN1; SMN2L3MBTL1DRD2HTR1A | |
| SCHEMBL11484395 | 0.69 | L3MBTL1 (0.63) | MAPK1SMN1; SMN2L3MBTL1DRD2 | |
| SCHEMBL7295187 | 0.69 | L3MBTL1 (0.70) | MAPK1SMN1; SMN2L3MBTL1DRD2HTR1A | |
| SCHEMBL9485683 | 0.68 | L3MBTL1 (0.68) | MAPK1SMN1; SMN2L3MBTL1DRD2HTR1A | |
| SCHEMBL2151191 | 0.68 | MAPK1 (0.77) | MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14430479 | 0.67 | MAPK1 (0.61) | MAPK1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3719280-A | 1,2,3 12A-TITRAHYDRO-7(2H)PLAIDOMENONES | SANDOZ AG | 1973-03-06 | — | — | US | disclosed |