SCHEMBL11883680

SCHEMBL11883680

O=C(Cn1ccnc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HMOX2 P30519 1/20 0.68
ALDH1A1 P00352 1/20 0.56
CYP19A1 P11511 3/20 0.55
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
TBXAS1 P24557 1/20 0.53
QPCT Q16769 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10250646 0.86 CYP19A1 (0.59) HMOX2CYP19A1TBXAS1QPCT
Hydrochloric Acid SCHEMBL410504 0.85 CYP19A1 (0.57) HMOX2CYP19A1TBXAS1QPCT
SCHEMBL28466107 0.84 HMOX2 (0.65) HMOX2ALDH1A1CYP19A1CYP3A4CYP2D6
SCHEMBL12045401 0.81 HMOX2 (1.00) HMOX2ALDH1A1CYP19A1CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL9996054 0.80 HMOX2 (0.97) HMOX2ALDH1A1CYP19A1CYP3A4CYP2D6
SCHEMBL10652258 0.78 CYP19A1 (0.69) HMOX2CYP19A1CYP3A4CYP2D6TBXAS1
SCHEMBL1509735 0.77 CYP19A1 (0.71) ALDH1A1CYP19A1TBXAS1
Biphenyl SCHEMBL27824074 0.77 ALDH1A1 (0.76) HMOX2ALDH1A1CYP19A1
SCHEMBL7082419 0.76 TBXAS1 (0.67) HMOX2CYP19A1TBXAS1
Hydrochloric Acid SCHEMBL410578 0.75 CYP19A1 (0.69) ALDH1A1CYP19A1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3755349-A ALPHA-SUBSTITUTED BENZYL-IMIDAZOLES BAYER AG 1973-08-28 US disclosed