Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | CASP1 | P29466 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | FLT1 | P17948 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5732135 | 1.00 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL9823673 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL180845 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL30185351 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL195020 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL8065539 | 0.83 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL654794 | 0.83 | ALDH1A1 (0.52) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL19998346 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL111279 | 0.81 | TSHR (1.00) | SMN1; SMN2TSHRCASP1MAPTKDM4E | |
| SCHEMBL699001 | 0.81 | ALDH1A1 (0.68) | SMN1; SMN2TSHRCASP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1924 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12161116-B1 | Ethyl-2-{[(2,4-dichlorobenzoyl carbamothioyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate as an eco-friendly insecticidal agent against Spodoptera littoralis (boisd.) | King Faisal University (SA) | 2024-12-10 | — | — | US | claimed |
| CN-113582836-B | Method for synthesizing 2, 4-dichlorobenzoyl chloride | 江苏聚由新材料科技有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-109384699-B | On-line full continuous flow production process for directly preparing organic peroxide by taking hydrogen peroxide as raw material | 上海惠和化德生物科技有限公司 | 2024-10-22 | — | — | CN | claimed |
| CN-118255720-A | Method for preparing imidazole ethanol | 启农生物科技(北京)有限公司 | 2024-06-28 | — | — | CN | claimed |
| CN-117471012-A | Method for detecting related substances of p-chlorobenzoyl chloride by gas chromatography | 南京医科大学康达学院 | 2024-01-30 | — | — | CN | claimed |
| CN-114249644-B | 2, 4-dichlorobenzoyl chloride production method and tail gas treatment process | 江苏万隆化学有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-117342946-A | Green treatment process for bis (2, 4-dichlorobenzoyl) peroxide mother liquor | 江苏强盛功能化学股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-116640056-A | Synthesis and byproduct purification method of 2, 4-dichlorobenzoyl chloride | 湖北联昌新材料有限公司 | 2023-08-25 | — | — | CN | claimed |
| CN-114057710-B | Silybin chemical modifier with anti-tumor activity and preparation method thereof | 沈阳化工大学 | 2023-08-01 | — | — | CN | claimed |
| CN-116375577-A | Production process of 2, 4-dichlorotoluene derivative | 济源市恒顺新材料有限公司 | 2023-07-04 | — | — | CN | claimed |
| US-6369246-B2 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS | DR. KEITH CHAN, GLOBOASIA, LLC | 2002-04-09 | — | — | US | claimed |
| US-20010018539-A1 | Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs | CHAN, KEITH | 2001-08-30 | — | — | US | claimed |
| EP-1058679-A1 | SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO AND ANALOGUES THEROF | Sloan-Kettering Institute For Cancer Research (US) | 2000-12-13 | — | — | EP | claimed |
| WO-2000061536-A2 | SYNTHESIS AND PHARMACEUTICALS OF NOVEL 9-SUBSTITUTED-1,5-DICHLOROANTHRACENE ANALOGS | GLOBOASIA, L.L.C. (US) | 2000-10-19 | — | — | WO | claimed |
| WO-1999043653-A1 | SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO AND ANALOGUES THEROF | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1999-09-02 | — | — | WO | claimed |
| EP-0639559-B1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM & HAAS (US) | 1997-10-15 | — | — | EP | claimed |
| CN-1126208-A | 2-amido-5-aryl-1,3,4-oxdiazole compound, its synthesis and application | HUADONG SCIENCE & ENGINEERING (CN) | 1996-07-10 | — | — | CN | claimed |
| EP-0639559-A1 | Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines | ROHM AND HAAS COMPANY (US) | 1995-02-22 | — | — | EP | claimed |
| EP-0440329-A1 | S-substituted carbonyl substituted betathioacrylamide biocides and fungicides | ROHM AND HAAS COMPANY (US) | 1991-08-07 | — | — | EP | claimed |
| US-4847442-A | Process for the preparation of difluorobenzenes | ALLIED-SIGNAL INC. (US) | 1989-07-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12161116-B1 | Ethyl-2-{[(2,4-dichlorobenzoyl carbamothioyl]amino}-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate as an eco-friendly insecticidal agent against Spodoptera littoralis (boisd.) | DDT, L3MBTL4, ABAT | SMN1; SMN2 2086/4885TSHR 2013/4885CASP1 375/4885 |
| US-20010018539-A1 | Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs | C3AR1, C5AR2, TLR2 | SMN1; SMN2 4829/4885TSHR 2549/4885CASP1 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.