Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 9/20 | 0.72 |
| ▸ | CDC25A | P30304 | 6/20 | 0.72 |
| ▸ | MAP2K7 | O14733 | 4/20 | 0.72 |
| ▸ | S100A4 | P26447 | 7/20 | 0.62 |
| ▸ | APAF1 | O14727 | 3/20 | 0.60 |
| ▸ | TDP2 | O95551 | 3/20 | 0.60 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30996023 | 1.00 | CDC25B (0.72) | CDC25BCDC25AMAP2K7S100A4APAF1 | |
| SCHEMBL1287111 | 0.84 | CDC25B (1.00) | CDC25BCDC25AMAP2K7S100A4APAF1 | |
| SCHEMBL30996022 | 0.79 | CDC25B (0.68) | CDC25BCDC25AMAP2K7S100A4APAF1 | |
| SCHEMBL2599369 | 0.77 | S100A4 (1.00) | CDC25BCDC25AMAP2K7S100A4APAF1 | |
| SCHEMBL461648 | 0.77 | APAF1 (1.00) | CDC25BS100A4APAF1TDP2APEX1 | |
| SCHEMBL29678361 | 0.77 | APAF1 (1.00) | CDC25BS100A4APAF1TDP2APEX1 | |
| SCHEMBL11573754 | 0.75 | CDC25B (0.72) | CDC25BCDC25AMAP2K7S100A4APAF1 | |
| SCHEMBL20532817 | 0.72 | APAF1 (0.89) | CDC25BS100A4APAF1TDP2MEN1 | |
| SCHEMBL30996031 | 0.72 | SOAT1 (0.56) | CDC25BCDC25AMAP2K7S100A4APAF1 | |
| SCHEMBL14232080 | 0.72 | CDC25A (0.67) | CDC25BCDC25AMAP2K7S100A4APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3912767-A | Novel sulfonate esters of 2-hydroxy-3-(methylthio)-1,4-naphthoquinone | AMERICAN CYANAMID CO | 1975-10-14 | — | — | US | disclosed |
| US-3912767-A | Novel sulfonate esters of 2-hydroxy-3-(methylthio)-1,4-naphthoquinone | AMERICAN CYANAMID CO | 1975-10-14 | — | — | US | disclosed |