Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 2/20 | 0.67 |
| ▸ | CDC25B | P30305 | 2/20 | 0.67 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.67 |
| ▸ | S100A4 | P26447 | 2/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.50 |
| ▸ | FGFR2 | P21802 | 4/20 | 0.50 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.50 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287111 | 0.81 | CDC25B (1.00) | CDC25ACDC25BMAP2K7S100A4MAPT | |
| SCHEMBL7878297 | 0.77 | PTGS2 (0.62) | CDC25ACDC25BMAP2K7FGFR1FGFR2 | |
| SCHEMBL740371 | 0.74 | FGFR1 (0.61) | CDC25ACDC25BS100A4FGFR1FGFR2 | |
| SCHEMBL5497788 | 0.74 | MAPT (0.65) | CDC25ACDC25BS100A4FGFR1FGFR2 | |
| SCHEMBL2599369 | 0.74 | S100A4 (1.00) | CDC25ACDC25BMAP2K7S100A4MAPT | |
| SCHEMBL5138652 | 0.74 | CDC25B (0.58) | CDC25ACDC25BS100A4FGFR1FGFR2 | |
| SCHEMBL11573754 | 0.72 | CDC25B (0.72) | CDC25ACDC25BMAP2K7S100A4MAPT | |
| SCHEMBL11884727 | 0.72 | CDC25B (0.72) | CDC25ACDC25BMAP2K7S100A4MAPT | |
| SCHEMBL30996023 | 0.72 | CDC25B (0.72) | CDC25ACDC25BMAP2K7S100A4MAPT | |
| SCHEMBL17250427 | 0.72 | MAPT (0.53) | CDC25ACDC25BMAP2K7S100A4FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008037604-A1 | NOVEL POLYBENZOFULVENE DERIVATIVES, SYNTHESIS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DI SIENA (IT) | 2008-04-03 | — | — | WO | disclosed |