Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.68 |
| ▸ | GAA | P10253 | 8/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.68 |
| ▸ | GLA | P06280 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | STS | P08842 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.58 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7046774 | 0.84 | ALDH1A1 (0.66) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| Hymecromone Methyl Ether SCHEMBL31103478 | 0.81 | KDM4E (1.00) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| Hymecromone Methyl Ether SCHEMBL314248 | 0.81 | KDM4E (1.00) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL31281633 | 0.80 | KDM4E (1.00) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL14176760 | 0.80 | KDM4E (1.00) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL3757479 | 0.80 | ALDH1A1 (0.73) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL335474 | 0.79 | KDM4E (1.00) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL29651337 | 0.79 | KDM4E (1.00) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL15842390 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KDM4EGAAHSD17B10GLA | |
| SCHEMBL12986857 | 0.78 | ALDH1A1 (0.76) | ALDH1A1KDM4EGAAHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138729-A1 | Coumarin Derivatives of Sugar Analogs and Uses Thereof | Rubedo Life Sciences, Inc. | 2023-05-04 | — | — | US | disclosed |
| US-11584752-B2 | Method for controlled release using mechanical force | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20170368188-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2017-12-28 | — | — | US | disclosed |
| US-20170202974-A1 | LINKERS AND THEIR APPLICATION TOWARDS ADC | MEDSHINE DISCOVERY INC. (CN) | 2017-07-20 | — | — | US | disclosed |
| US-20150011512-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2015-01-08 | — | — | US | disclosed |
| US-20120302748-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2012-11-29 | — | — | US | disclosed |
| US-20120190639-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138729-A1 | Coumarin Derivatives of Sugar Analogs and Uses Thereof | GLA, ENGASE, GLB1 | ALDH1A1 706/4885KDM4E 1803/4885GAA 19/4885 |
| US-20120302748-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | BRCA1, CYP1B1, UGT1A1 | ALDH1A1 35/4885KDM4E 4346/4885GAA 980/4885 |
| US-20120190639-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, UGT1A1, CYP1A1 | ALDH1A1 55/4885KDM4E 3646/4885GAA 1092/4885 |
| US-20170202974-A1 | LINKERS AND THEIR APPLICATION TOWARDS ADC | DNPEP, DPP7, DPP3 | ALDH1A1 400/4885KDM4E 1505/4885GAA 6/4885 |
| US-11584752-B2 | Method for controlled release using mechanical force | DYNLL2, PARP12, RUVBL2 | ALDH1A1 2079/4885KDM4E 3001/4885GAA 4343/4885 |
| US-20170368188-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, UGT1A1, CYP1A1 | ALDH1A1 61/4885KDM4E 3979/4885GAA 1038/4885 |
| US-20150011512-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, UGT1A1, CYP1A1 | ALDH1A1 55/4885KDM4E 3646/4885GAA 1092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.