SCHEMBL335474

SCHEMBL335474

CC(=O)Oc1ccc2c(C)cc(=O)oc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 1.00
ALDH1A1 P00352 10/20 1.00
GAA P10253 10/20 1.00
GLA P06280 9/20 1.00
HSD17B10 Q99714 5/20 0.71
HPGD P15428 4/20 0.71
KMT2A Q03164 3/20 0.71
MAPT P10636 4/20 0.69
NPBWR1 P48145 1/20 0.69
F2 P00734 1/20 0.66
CASP1 P29466 3/20 0.64
CASP7 P55210 3/20 0.64
HSP90AA1 P07900 1/20 0.64
HSP90AB1 P08238 1/20 0.64
ALPG P10696 1/20 0.64
ALOX15 P16050 1/20 0.64
ALOX12 P18054 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
CA12 O43570 2/20 0.61
CA9 Q16790 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29651337 1.00 KDM4E (1.00) KDM4EALDH1A1GAAGLAHSD17B10
SCHEMBL6994348 0.88 KDM4E (0.78) KDM4EALDH1A1GAAGLAHSD17B10
SCHEMBL27788739 0.87 ALDH1A1 (0.77) KDM4EALDH1A1GAAGLAHSD17B10
SCHEMBL18917474 0.87 ALDH1A1 (0.76) KDM4EALDH1A1GAAGLAHSD17B10
SCHEMBL12986857 0.87 ALDH1A1 (0.76) KDM4EALDH1A1GAAGLAHSD17B10
SCHEMBL7920869 0.86 ALDH1A1 (0.75) KDM4EALDH1A1GAAGLAHSD17B10
SCHEMBL30862481 0.86 ALDH1A1 (0.75) KDM4EALDH1A1GAAGLAHSD17B10
SCHEMBL1395030 0.85 KDM4E (0.74) KDM4EALDH1A1GAAGLAHSD17B10
SCHEMBL12986854 0.84 ALDH1A1 (0.72) KDM4EALDH1A1GAAGLAHSD17B10
SCHEMBL2534958 0.84 ALDH1A1 (0.82) KDM4EALDH1A1GAAGLAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 714 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083363-A1 LUMINESCENT ENZYME-BASED SENSORS TERUMO CARDIOVASCULAR SYS CORP (US) 2026-03-26 US claimed
CN-118419950-A Preparation method of high-quality Prussian blue compound (PB) and analogue (PBA) thereof for positive electrode of sodium ion battery 电子科技大学 2024-08-02 CN claimed
CN-117871508-A Reagent card for rapidly detecting pesticide residues and pesticide residue detection method 苏州慧源安食检测科技有限公司 2024-04-12 CN claimed
WO-2024059143-A1 LUMINESCENT ENZYME-BASED SENSORS TERUMO CARDIOVASCULAR SYSTEMS CORPORATION (US) 2024-03-21 WO claimed
CN-116338054-A Detection method of aflatoxin B1 in traditional Chinese medicine based on liquid chromatography 广东维安检测科技有限公司 2023-06-27 CN claimed
US-20230184763-A1 METHOD OF DETECTING VIRUS HAVING HEMAGGLUTININ-ESTERASE ACTIVITY LEE JI HOON (US) 2023-06-15 US claimed
CN-111471147-B Double-template molecular amino functionalized metal organic framework imprinted polymer, and synthetic method and application thereof 河南水利与环境职业学院 2022-12-09 CN claimed
CN-115298548-A Method for detecting viruses having hemagglutinin esterase activity 李知勋 2022-11-04 CN claimed
EP-4053206-A1 A METHOD FOR THE PREPARATION OF A HYBRID NANO-STRUCTURED COMPOSITE COMPRISING CELLULOSE NANO-PARTICLES AND METAL COMPOUND NANO-PARTICLES Fruitful Innovations BV (NL) 2022-09-07 EP claimed
CN-110596083-B Reagent and card for detecting organophosphorus and carbamate pesticide residues 广州聚佰生物科技有限公司 2021-10-15 CN claimed
US-6465162-B1 Photothermographic materials containing backside image stabilizing compounds EASTMAN KODAK COMPANY 2002-10-15 US claimed
US-6368778-B1 FLUORENONE, FLUORENE, COUMARIN, NAPHTHALIC ACID IMIDE, PYRAZOLINE, OR ANTHRACENE IMAGE STABILIZER COMPOUNDS IN THE SILVER LAYER REDUCE IMAGE BROWNING; STABLE TO LIGHT AND HEAT OVER TIME PARTICULARLY UNDER LIGHT-BOX CONDITIONS EASTMAN KODAK COMPANY 2002-04-09 US claimed
EP-1044205-A4 CHEMICAL ACETYLATION OF DESACETYL-CEPHALOSPORINS BRISTOL MYERS SQUIBB CO (US) 2001-12-05 EP claimed
EP-1044205-A1 CHEMICAL ACETYLATION OF DESACETYL-CEPHALOSPORINS Bristol-Myers Squibb Company (US) 2000-10-18 EP claimed
US-5917032-A ACETYL DONOR AND DICYCLOHEXYLAMINE ACTIVATOR OR CATALYST. BRISTOL-MYERS SQUIBB COMPANY (US) 1999-06-29 US claimed
WO-1999023098-A1 CHEMICAL ACETYLATION OF DESACETYL-CEPHALOSPORINS BRISTOL-MYERS SQUIBB COMPANY (US) 1999-05-14 WO claimed
US-5094944-A Umbelliferyl containing substrates HAYES KENNETH R (US) 1992-03-10 US claimed
WO-1990012886-A1 FLUORESCENT AQUATIC BIOASSAY AND PROCEDURE HAYES KENNETH R (US) 1990-11-01 WO claimed
US-4868110-A Methods and device for detection of microorganisms BIOCONTROL SYSTEMS, INC. (US) 1989-09-19 US claimed
EP-0264221-A2 Methods and device for detection of microorganisms BioControl Systems, Inc. (US) 1988-04-20 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083363-A1 LUMINESCENT ENZYME-BASED SENSORS AOX1, XDH, LPO KDM4E 2545/4885ALDH1A1 96/4885GAA 60/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.