Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837577 | 0.81 | CYP3A4 (0.57) | ALOX15CYP3A4HIF1AHSD17B10ESR1 | |
| SCHEMBL837801 | 0.79 | CYP3A4 (0.50) | NR1H2ALOX15CYP3A4HIF1AHSD17B10 | |
| SCHEMBL13252232 | 0.78 | CYP3A4 (0.46) | ALOX15CYP3A4HIF1AHSD17B10MEN1 | |
| SCHEMBL19865715 | 0.78 | NR1H2 (0.46) | NR1H2ALOX15CYP3A4HIF1AHSD17B10 | |
| SCHEMBL761140 | 0.78 | ACHE (0.38) | HSD17B10MEN1KMT2AALDH1A1CA2 | |
| SCHEMBL12193584 | 0.78 | MAPT (0.43) | ALOX15CYP3A4HSD17B10MEN1KMT2A | |
| SCHEMBL2734944 | 0.78 | ORAI1 (0.32) | MEN1KMT2ACA2CA1CA9 | |
| SCHEMBL10099509 | 0.77 | HPGD (0.41) | ALOX15HSD17B10ALDH1A1CA2CA3 | |
| SCHEMBL583468 | 0.76 | NR1H2 (0.55) | NR1H2ALOX15CYP3A4HIF1AHSD17B10 | |
| SCHEMBL14588715 | 0.75 | CA1 (0.48) | CYP3A4ALDH1A1CA2CA14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455176-B2 | Coating composition | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2013-06-04 | — | — | US | disclosed |
| US-8367828-B2 | PPAR active compounds | PLEXXIKON INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8227621-B2 | Cyanine dyes and methods of use | LI-COR, INC. (US) | 2012-07-24 | — | — | US | disclosed |
| US-20100210036-A1 | PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. | 2010-08-19 | — | — | US | disclosed |
| US-7723374-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2010-05-25 | — | — | US | disclosed |
| US-20100119972-A1 | COATING COMPOSITION | MERCK PATENT GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
| US-20100080758-A1 | OPTICAL FLUORESCENT IMAGING | LI-COR,INC. (US) | 2010-04-01 | — | — | US | disclosed |
| US-7597878-B2 | Optical fluorescent imaging | LI-COR, INC. (US) | 2009-10-06 | — | — | US | disclosed |
| US-7572806-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2009-08-11 | — | — | US | disclosed |
| US-7504089-B2 | Cyanine dyes | LI-COR, INC. (US) | 2009-03-17 | — | — | US | disclosed |
| US-7491831-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2009-02-17 | — | — | US | disclosed |
| US-7476746-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20080096913-A1 | PPAR active compounds | PLEXXIKON, INC. | 2008-04-24 | — | — | US | disclosed |
| US-7348338-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2008-03-25 | — | — | US | disclosed |
| US-20080045581-A1 | PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. | 2008-02-21 | — | — | US | disclosed |
| US-20070155818-A1 | PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070149603-A1 | PPAR ACTIVE COMPOUNDS | PLEXXIKON, INC. | 2007-06-28 | — | — | US | disclosed |
| US-7202266-B2 | PPAR active compounds | PLEXXIKON, INC. (US) | 2007-04-10 | — | — | US | disclosed |
| US-20070042398-A1 | CYANINE DYES AND METHODS OF USE | LI-COR, INC. (US) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080096913-A1 | PPAR active compounds | PPARG, PPARD, PPARA | NR1H2 15/4885ALOX15 694/4885CYP3A4 553/4885 |
| US-20100080758-A1 | OPTICAL FLUORESCENT IMAGING | FCGR2A, CD69, FOLR1 | NR1H2 975/4885ALOX15 1249/4885CYP3A4 3343/4885 |
| US-20080045581-A1 | PPAR ACTIVE COMPOUNDS | PPARG, PPARD, PPARA | NR1H2 15/4885ALOX15 694/4885CYP3A4 553/4885 |
| US-20070042398-A1 | CYANINE DYES AND METHODS OF USE | CRY2, IK, CRY1 | NR1H2 3067/4885ALOX15 3429/4885CYP3A4 103/4885 |
| US-20070149603-A1 | PPAR ACTIVE COMPOUNDS | PPARG, PPARD, PPARA | NR1H2 15/4885ALOX15 694/4885CYP3A4 553/4885 |
| US-20100210036-A1 | PPAR ACTIVE COMPOUNDS | PPARG, PPARD, PPARA | NR1H2 15/4885ALOX15 694/4885CYP3A4 553/4885 |
| US-20100119972-A1 | COATING COMPOSITION | S100A9, CAPG, C5 | NR1H2 2208/4885ALOX15 3105/4885CYP3A4 4514/4885 |
| US-20070155818-A1 | PPAR ACTIVE COMPOUNDS | PPARG, PPARD, PPARA | NR1H2 15/4885ALOX15 694/4885CYP3A4 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.