SCHEMBL583468

SCHEMBL583468

Oc1ccc(SOSc2ccc(O)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 2/20 0.55
ALOX15 P16050 4/20 0.47
CYP3A4 P08684 3/20 0.47
HIF1A Q16665 3/20 0.47
HSD17B10 Q99714 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
CA2 P00918 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CA3 P07451 2/20 0.47
CA14 Q9ULX7 2/20 0.47
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
CA12 O43570 1/20 0.47
GMNN O75496 1/20 0.47
CA1 P00915 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
TYR P14679 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2303871 0.78 NR1H2 (0.50) NR1H2ALOX15CYP3A4HIF1AHSD17B10
SCHEMBL11887231 0.76 NR1H2 (0.48) NR1H2ALOX15CYP3A4HIF1AHSD17B10
SCHEMBL19865715 0.74 NR1H2 (0.46) NR1H2ALOX15CYP3A4HIF1AHSD17B10
SCHEMBL8568584 0.73
SCHEMBL10914949 0.71 NR1H2 (1.00) NR1H2ALOX15CYP3A4HIF1AHSD17B10
SCHEMBL901003 0.71 NR1H2 (0.65) NR1H2ALOX15CYP3A4HIF1AHSD17B10
SCHEMBL29726 0.71 NR1H2 (1.00) NR1H2ALOX15CYP3A4HIF1AHSD17B10
SCHEMBL3628062 0.71 NR1H2 (0.42) NR1H2ALOX15CYP3A4HIF1AHSD17B10
SCHEMBL7183452 0.71 CA1 (0.36) MEN1KMT2ACA2ALDH1A1CA1
SCHEMBL14685179 0.71 ACHE (0.47) CYP3A4MEN1KMT2ACA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107108874-B Polycarbonate copolymer and method for producing same 株式会社三养社 2019-08-30 CN claimed
CN-109563336-A Polycarbonate compositions and articles comprising the same 株式会社LG化学 2019-04-02 CN claimed
CN-106795286-A Heat resistance and the excellent polysulfone copolymer of chemical resistance and preparation method thereof 株式会社三养社 2017-05-31 CN claimed
CN-105980446-A Polycarbonate composition and article comprising same LG化学株式会社 2016-09-28 CN claimed
CN-105940035-A Copolycarbonate composition and articles containing the same 株式会社LG化学 2016-09-14 CN claimed
CN-105899575-A Copolycarbonate and composition containing same LG化学株式会社 2016-08-24 CN claimed
CN-105899574-A Copolycarbonate and composition containing same LG化学株式会社 2016-08-24 CN claimed
CN-105899576-A Copolycarbonate and composition containing same LG化学株式会社 2016-08-24 CN claimed
CN-105899611-A Copolycarbonate resin composition LG化学株式会社 2016-08-24 CN claimed
CN-105899573-A Copolycarbonate and composition comprising same LG化学株式会社 2016-08-24 CN claimed
CN-1938379-A Impact-modified compositions and methods GEN ELECTRIC (US) 2007-03-28 CN claimed
WO-2007006300-A1 PRODUCTION OF MONOMER, OLIGOMER AND POLYMER PHOSPHONIC ACID ESTERS AND PHOSPHONIC AND SULPHONIC ACIDS BY A NUCLEOPHILE AROMATIC SUBSTITUTION Universität Stuttgart (DE) 2007-01-18 WO claimed
CN-1871195-A Method for making salts hydroxy-substituted hydrocarbons GEN ELECTRIC (US) 2006-11-29 CN claimed
CN-1273515-C Melt polycarbonate catalyst system GEN ELECTRIC (US) 2006-09-06 CN claimed
WO-2006066569-A2 IONOMERS AND IONOMER BLENDS BASED ON PARTIALLY FLUORINATED POLY(HETERO)ARYLS HÄRING, Thomas (DE) 2006-06-29 WO claimed
CN-1224635-C High refractive index thermoplastic polyphosphonates JOHNSON & JOHNSON VISION CARE (US) 2005-10-26 CN claimed
CN-1541239-A Melt Polycarbonate Catalyst System ͨ�õ�����˾ 2004-10-27 CN claimed
CN-1500105-A Melt polycarbonate catalyst systems ͨ�õ�����˾ 2004-05-26 CN claimed
CN-1492897-A Melt polycarbonate catalyst system ͨ�õ�����˾ 2004-04-28 CN claimed
CN-1387545-A High refractive index thermoplastic polyphosphonates JOHNSON & JOHNSON VISION CARE (US) 2002-12-25 CN claimed