Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | PRKX | P51817 | 2/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | PLK4 | O00444 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18669180 | 0.80 | NOS1 (0.60) | HDAC6GLAL3MBTL1NOS1HSD17B10 | |
| SCHEMBL7571385 | 0.76 | GLA (0.55) | HDAC6GLAL3MBTL1NOS1HSD17B10 | |
| SCHEMBL15427016 | 0.76 | BRD4 (0.57) | HDAC6GLAL3MBTL1NOS1PRKX | |
| SCHEMBL11577556 | 0.76 | GLA (0.54) | HDAC6GLAL3MBTL1LMNANOS1 | |
| SCHEMBL17738544 | 0.75 | TDO2 (0.59) | HDAC6LMNAROCK1CLK4ROCK2 | |
| SCHEMBL5948731 | 0.74 | NR3C1 (0.47) | HDAC6HSD17B10BACE1GSK3BKDM4E | |
| SCHEMBL20239491 | 0.73 | GLA (0.63) | HDAC6GLAL3MBTL1NOS1HSD17B10 | |
| SCHEMBL21863628 | 0.73 | GLA (0.58) | HDAC6GLAL3MBTL1NOS1HSD17B10 | |
| SCHEMBL10805500 | 0.73 | SLC2A1 (0.49) | LMNAHSD17B10PLK4KDM4EHPGD | |
| SCHEMBL4571036 | 0.71 | HSD17B10 (0.71) | L3MBTL1HSD17B10BACE1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479236-A1 | Indazole compound-containing composition and light-emitting device using the composition | SUMITOMO CHEMICAL CO., LTD. (JP) | 2012-07-25 | — | — | EP | disclosed |
| US-20100032624-A1 | INDAZOLE COMPOUND-CONTAINING COMPOSITION AND LIGHT-EMITTING DEVICE USING THE COMPOSITION | SUMITOMO CHEMCIAL COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20100032624-A1 | INDAZOLE COMPOUND-CONTAINING COMPOSITION AND LIGHT-EMITTING DEVICE USING THE COMPOSITION | SUMITOMO CHEMCIAL COMPANY, LIMITED (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-2119753-A1 | INDAZOLE COMPOUND-CONTAINING COMPOSITION AND LIGHT-EMITTING DEVICE USING THE COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2009-11-18 | — | — | EP | disclosed |