Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 5/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | MMP2 | P08253 | 3/20 | 0.61 |
| ▸ | MMP3 | P08254 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806438 | 0.77 | SMN1; SMN2 (0.83) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL6823156 | 0.76 | MMP2 (1.00) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL12808152 | 0.75 | ALDH1A1 (0.70) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL5702949 | 0.75 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| Hydroxyamine SCHEMBL8164284 | 0.74 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL7207785 | 0.74 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL12808273 | 0.73 | ALDH1A1 (0.67) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL806760 | 0.71 | SMN1; SMN2 (0.75) | SMN1; SMN2LMNAMAPTKMT2AGAA | |
| SCHEMBL5703157 | 0.71 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL15617705 | 0.71 | NPC1 (0.69) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9101635-B2 | Inhibitors of filovirus entry into host cells | MICROBIOTIX, INC. (US) | 2015-08-11 | — | — | US | disclosed |
| US-20120189614-A1 | INHIBITORS OF FILOVIRUS ENTRY INTO HOST CELLS | Crobiotix, Inc. (US) | 2012-07-26 | — | — | US | disclosed |
| WO-2011046646-A2 | INHIBITORS OF FILOVIRUS ENTRY INTO HOST CELLS | MICROBIOTIX, INC. (US) | 2011-04-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120189614-A1 | INHIBITORS OF FILOVIRUS ENTRY INTO HOST CELLS | BSG, SLCO1B3, SLCO2B1 | PDE4A 3993/4885PDE4B 4411/4885PDE4C 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.