Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12696828 | 0.91 | GRM5 (0.38) | GRM5CA12CA2CA9KCNH2 | |
| SCHEMBL11891673 | 0.88 | ACHE (0.48) | GRM5CA12CA2CA9KCNH2 | |
| SCHEMBL19790006 | 0.86 | KCNH2 (0.34) | GRM5CA12CA2CA9KCNH2 | |
| SCHEMBL19790048 | 0.86 | APP (0.48) | GRM5CA12CA2CA9KCNH2 | |
| SCHEMBL19308574 | 0.84 | GRM5 (0.52) | GRM5CA12CA2CA9KCNH2 | |
| SCHEMBL7857715 | 0.84 | GRM5 (0.41) | GRM5CA12CA2CA9KCNH2 | |
| SCHEMBL12892514 | 0.84 | GRM5 (0.41) | GRM5CA12CA2CA9KCNH2 | |
| SCHEMBL4567628 | 0.81 | GRM5 (0.39) | GRM5CA12CA2CA9KCNH2 | |
| SCHEMBL9510036 | 0.81 | GRM5 (0.39) | GRM5CA12CA2CA9KCNH2 | |
| SCHEMBL19789971 | 0.81 | APP (0.39) | GRM5CA12CA2CA9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200262795-A1 | CYANOPYRIMIDINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-08-20 | — | — | US | disclosed |
| US-10442990-B2 | Mesogenic compounds, liquid crystal media and components for high frequency technology | MERCK PATENT GMBH (DE) | 2019-10-15 | — | — | US | disclosed |
| US-9938462-B2 | Liquid-crystalline media, components for high-frequency technology, and mesogenic compounds | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9938462-B2 | Liquid-crystalline media, components for high-frequency technology, and mesogenic compounds | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| WO-2017162707-A1 | CYANOPYRIMIDINE DERIVATIVES SUITABLE AS COMPONENTS IN LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2017-09-28 | — | — | WO | disclosed |
| US-9765259-B2 | Mesogenic compounds, liquid-crystalline media and components for high-frequency technology | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| US-9765259-B2 | Mesogenic compounds, liquid-crystalline media and components for high-frequency technology | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| US-9752077-B2 | Liquid-crystalline media, components for high-frequency technology, and mesogenic compounds | MERCK PATENT GMBH (DE) | 2017-09-05 | — | — | US | disclosed |
| US-9752077-B2 | Liquid-crystalline media, components for high-frequency technology, and mesogenic compounds | MERCK PATENT GMBH (DE) | 2017-09-05 | — | — | US | disclosed |
| US-9523037-B2 | Liquid-crystalline media, components for high-frequency technology, and mesogenic compounds | MERCK PATENT GMBH (DE) | 2016-12-20 | — | — | US | disclosed |
| US-9296948-B2 | Mesogenic compounds, liquid-crystalline media and components for high-frequency technology | MERCK PATENT GMBH (DE) | 2016-03-29 | — | — | US | disclosed |
| US-20160002533-A1 | LIQUID-CRYSTALLINE MEDIA, COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-01-07 | — | — | US | disclosed |
| US-20150322344-A1 | LIQUID-CRYSTALLINE MEDIA, COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2015-11-12 | — | — | US | disclosed |
| WO-2014094973-A1 | LIQUID-CRYSTALLINE MEDIA, COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
| US-20140021405-A1 | MESOGENIC COMPOUNDS, LIQUID-CRYSTALLINE MEDIA AND COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY | MERCK PATENT GMBH (DE) | 2014-01-23 | — | — | US | disclosed |
| US-20140021409-A1 | MESOGENIC COMPOUNDS, LIQUID-CRYSTALLINE MEDIA AND COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY | MERCK PATENT GMBH (DE) | 2014-01-23 | — | — | US | disclosed |
| US-20130292608-A1 | LIQUID-CRYSTALLINE MEDIA, COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2013-11-07 | — | — | US | disclosed |
| WO-2012126563-A1 | MESOGENIC COMPOUNDS, LIQUID CRYSTAL MEDIA AND COMPONENTS FOR HIGH FREQUENCY TECHNOLOGY | MERCK PATENT GMBH (DE) | 2012-09-27 | — | — | WO | disclosed |
| WO-2012126565-A1 | MESOGENIC COMPOUNDS, LIQUID CRYSTAL MEDIA, AND COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY | MERCK PATENT GMBH (DE) | 2012-09-27 | — | — | WO | disclosed |
| WO-2012097853-A1 | LIQUID CRYSTALLINE MEDIA, COMPONENTS FOR HIGH FREQUENCY TECHNOLOGY AND MESOGENIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2012-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322344-A1 | LIQUID-CRYSTALLINE MEDIA, COMPONENTS FOR HIGH-FREQUENCY TECHNOLOGY, AND MESOGENIC COMPOUNDS | MIF, SFRP1, MCM3 | GRM5 3161/4885CA12 212/4885CA2 587/4885 |
| US-20200262795-A1 | CYANOPYRIMIDINE DERIVATIVES | MCM6, MCM4, MCM2 | GRM5 2345/4885CA12 1247/4885CA2 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.