SCHEMBL11892467

SCHEMBL11892467

CCC(=O)CCOC(=O)CC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.52
TDP1 Q9NUW8 1/20 0.43
DGKA P23743 1/20 0.41
ALDH1A1 P00352 2/20 0.40
GAA P10253 2/20 0.40
ADRA2A P08913 1/20 0.39
ADRA1A P35348 1/20 0.39
DNM1 Q05193 1/20 0.38
BLM P54132 2/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C19 P33261 2/20 0.38
HPGD P15428 1/20 0.38
WRN Q14191 1/20 0.38
HIF1A Q16665 1/20 0.38
HTR2C P28335 1/20 0.37
KDM4E B2RXH2 1/20 0.37
MGAM O43451 1/20 0.35
SI P14410 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2610345 0.86 ALDH1A1 (0.54) NAAATDP1DGKAALDH1A1GAA
SCHEMBL27835739 0.84 NAAA (0.38) NAAATDP1DGKAALDH1A1GAA
SCHEMBL4939217 0.82 MGAM (0.39) NAAATDP1DGKAALDH1A1GAA
SCHEMBL27816111 0.82 DGKA (0.41) NAAATDP1DGKAALDH1A1GAA
SCHEMBL27878537 0.82 ALDH1A1 (0.46) NAAATDP1DGKAALDH1A1GAA
SCHEMBL50301 0.81 NAAA (0.64) NAAATDP1DGKAALDH1A1GAA
SCHEMBL2355681 0.80 NAAA (0.52) NAAADGKAALDH1A1GAAADRA2A
SCHEMBL7047113 0.80 ALDH1A1 (0.52) TDP1ALDH1A1GAAHTTSOAT1
SCHEMBL2479752 0.80 NAAA (0.52) NAAADGKAALDH1A1GAAADRA2A
SCHEMBL28460843 0.80 ALDH1A1 (0.52) NAAADGKAALDH1A1GAAADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676716-B2 Polycarbonate having improved thermal and mechanical properties and reduced coefficients of thermal expansion COVESTRO DEUTSCHLAND AG (DE) 2017-06-13 US disclosed
US-20140357767-A1 POLYCARBONATE COMPOSITIONS WITH IMPROVED MELT STABILITY BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-12-04 US disclosed
US-8664349-B2 Polycarbonate compositions having improved optical properties BAYER MATERIALSCIENCE AG (DE) 2014-03-04 US disclosed
US-8487025-B2 Branched melt polycarbonate with low content of defective structures BAYER MATERIAL SCIENCE AG (DE) 2013-07-16 US disclosed
US-8470934-B2 Polycarbonate compositions having improved surface hardness BAYER MATERIALSCIENCE AG (DE) 2013-06-25 US disclosed
US-20130123423-A1 POLYCARBONATE COMPOSITION HAVING IMPROVED OPTICAL AND THERMAL PROPERTIES COVESTRO DEUTSCHLAND AG (DE) 2013-05-16 US disclosed
US-20120232196-A1 UV-STABLE POLYCARBONATE COMPOSITION HAVING IMPROVED PROPERTIES BAYER MATERIALSCIENCE AG (DE) 2012-09-13 US disclosed
US-20120208936-A1 POLYCARBONATE COMPOSITIONS WITH IMPROVED MELT STABILITY BAYER MATERIALSCIENCE AG (DE) 2012-08-16 US disclosed
US-20120190778-A1 POLYCARBONATE COMPOSITIONS HAVING IMPROVED OPTICAL PROPERTIES BAYER MATERIALSCIENCE AG (DE) 2012-07-26 US disclosed
US-20110151262-A1 POLYCARBONATE HAVING IMPROVED THERMAL AND MECHANICAL PROPERTIES AND REDUCED COEFFICIENTS OF THERMAL EXPANSION BAYER MATERIALSCIENCE AG (DE) 2011-06-23 US disclosed
US-20110144283-A1 COPOLYCARBONATE COMPOSITIONS HAVING IMPROVED THERMAL PROPERTIES AND BASED ON BLENDS BAYER MATERIALSCIENCE AG (DE) 2011-06-16 US disclosed
US-20110008579-A1 MULTI-WALL SHEET WITHOUT THE TRIANGLE EFFECT, COATED BY COEXTRUSION BAYER MATERIALSCIENCE AG (DE) 2011-01-13 US disclosed
US-7824589-B2 Multi-wall sheet without the triangle effect, coated by coextrusion BAYER POLYMERS SHEET EUROPE GMBH (DE) 2010-11-02 US disclosed
US-7790287-B2 Light-scattering sheet having high light transmission and improved antistatic properties BAYER MATERIALSCIENCE AG (DE) 2010-09-07 US disclosed
US-7691477-B2 Polyformals as a coextrusion protective layer on polycarbonate BAYER MATERIALSCIENCE AG (DE) 2010-04-06 US disclosed
US-7582720-B2 Transparent polycarbonate, poly(meth)acrylate core/shell particles; free of anthanthrones, anthraquinones, benzimidazoles, diketopyrrolopyrroles, isoindolinols, perinones, perylenes, phthalocyanines, quinacridones, quinophthalones which prevents degradation of polycarbonate; diffuser sheets BAYER MATERIAL SCIENCE AG (DE) 2009-09-01 US disclosed
US-20070224367-A1 Mold multilayered sheet for use as a diffuser in flat screens BAYER MATERIALSCIENCE AG (DE) 2007-09-27 US disclosed
US-7226906-B2 Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases ARRAY BIOPHARMA, INC. (US) 2007-06-05 US disclosed
US-20070060704-A1 Light-scattering moldings with high light transmission BAYER MATERIALSCIENCE AG (DE) 2007-03-15 US disclosed
US-20070060681-A1 Light-scattering sheet having high light transmission and improved antistatic properties BAYER MATERIALSCIENCE AG (DE) 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110151262-A1 POLYCARBONATE HAVING IMPROVED THERMAL AND MECHANICAL PROPERTIES AND REDUCED COEFFICIENTS OF THERMAL EXPANSION PUF60, TEC, RPTOR NAAA 4484/4885TDP1 2353/4885DGKA 2943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.