Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28653419 | 0.86 | DGKA (0.44) | DGKAADRA2AADRA1AMAPTBLM | |
| SCHEMBL27835739 | 0.85 | NAAA (0.38) | DGKAADRA2AADRA1AMAPTBLM | |
| SCHEMBL2610345 | 0.83 | ALDH1A1 (0.54) | DGKAADRA2AADRA1AMAPTBLM | |
| SCHEMBL11892467 | 0.82 | NAAA (0.52) | DGKAADRA2AADRA1AMAPTBLM | |
| SCHEMBL27816310 | 0.81 | PAM (0.38) | DGKAADRA2AADRA1AMAPTBLM | |
| SCHEMBL130838 | 0.80 | — | — | |
| SCHEMBL27835797 | 0.78 | ADRA2A (0.41) | DGKAADRA2AADRA1AMAPTBLM | |
| SCHEMBL126972 | 0.77 | DGKA (0.57) | DGKAHTR2CNAAAALDH1A1DNM1 | |
| SCHEMBL131716 | 0.77 | — | — | |
| SCHEMBL19029984 | 0.76 | DGKA (0.74) | DGKAMAPTHTR2CNAAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102161641-A | Pyridone complex | SUMITOMO CO LTD | 2011-08-24 | — | — | CN | disclosed |
| CN-102134262-A | Pyridine ketone complex | SUMITOMO CO LTD | 2011-07-27 | — | — | CN | disclosed |