SCHEMBL11901195

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7325260	0.78	HPGD (0.46)	PTGS1ALDH1A1PTGS2TLR2TLR1
	SCHEMBL1260380	0.78	TLR2 (0.65)	PTGS1ALDH1A1PTGS2TLR2TLR1
	SCHEMBL11901049	0.78	TLR2 (0.48)	ALDH1A1PTGS2TLR2TLR1MEN1
	SCHEMBL5606561	0.77	PTGS2 (0.52)	PTGS1PTGS2
	SCHEMBL23884749	0.76	ALDH1A1 (0.38)	ALDH1A1
	SCHEMBL22465893	0.76	HTR2A (0.42)	ALDH1A1TLR2TLR1POLBHTR2A
	SCHEMBL1037500	0.76	HTT (0.51)	ALDH1A1TLR2TLR1POLBHTR2A
	SCHEMBL11899949	0.76	NR2E1 (0.42)	PTGS1PTGS2MAPT
	SCHEMBL8819363	0.76	PTGS2 (0.40)	PTGS1PTGS2
	SCHEMBL31314846	0.76	NPC1 (0.50)	PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.