Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | CDC14B | O60729 | 1/20 | 0.33 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL27085288 | 0.84 | ALOX5 (0.38) | MAOAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL12349444 | 0.82 | ALOX5 (0.38) | MAOAALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL26012060 | 0.78 | TDP1 (0.35) | MAOAALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL26026421 | 0.75 | PRKDC (0.36) | ALDH1A1KDM4EHPGDMAPTCYP3A4 | |
| SCHEMBL19389196 | 0.73 | CHRNA7 (0.43) | MAOAALDH1A1KDM4EHPGDMAPT | |
| Bromide SCHEMBL28205273 | 0.73 | HSD17B10 (0.41) | ALDH1A1KDM4EHPGDMAPTHSD17B10 | |
| SCHEMBL31678716 | 0.72 | GPR3 (0.36) | ALDH1A1KDM4EHPGDMAPTCYP3A4 | |
| SCHEMBL29814504 | 0.72 | GPR3 (0.36) | ALDH1A1KDM4EHPGDMAPTCYP3A4 | |
| SCHEMBL25635217 | 0.71 | PRKDC (0.34) | ALDH1A1KDM4EHPGDMAPTPRKDC | |
| SCHEMBL26248556 | 0.71 | PRKDC (0.37) | PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9108998-B2 | Dinuclear platinum-carbene complexes and the use thereof in OLEDs | BASF SE (DE) | 2015-08-18 | — | — | US | disclosed |
| US-20120199823-A1 | DINUCLEAR PLATINUM-CARBENE COMPLEXES AND THE USE THEREOF IN OLEDS | BASF SE (DE) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120199823-A1 | DINUCLEAR PLATINUM-CARBENE COMPLEXES AND THE USE THEREOF IN OLEDS | OCIAD1, OCIAD2, OXER1 | MAOA 2667/4885ALDH1A1 2775/4885KDM4E 4868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.