SCHEMBL12349444

SCHEMBL12349444

CN1C=CN(c2cccc3c2oc2ccccc23)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.38
MEN1 O00255 1/20 0.37
CYP2C19 P33261 1/20 0.37
KMT2A Q03164 1/20 0.37
DRD4 P21917 1/20 0.35
HRH4 Q9H3N8 2/20 0.34
PRKDC P78527 6/20 0.34
ALDH1A1 P00352 2/20 0.33
MAOA P21397 2/20 0.33
LMNA P02545 2/20 0.33
AHR P35869 1/20 0.33
PIK3CD O00329 1/20 0.33
PIK3CB P42338 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ATM Q13315 1/20 0.33
MAPT P10636 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL11901430 0.82 MAOA (0.34) PRKDCALDH1A1MAOAKDM4ENPC1
SCHEMBL24851124 0.82 ALOX5 (0.36) ALOX5MEN1CYP2C19KMT2ADRD4
SCHEMBL24851676 0.80 MEN1 (0.36) ALOX5MEN1CYP2C19KMT2ADRD4
SCHEMBL20752001 0.79 PGR (0.35) ALOX5MEN1CYP2C19KMT2ADRD4
SCHEMBL21362374 0.75 NPC1 (0.39) DRD4LMNANPC1RAB9AMAPT
SCHEMBL20732624 0.73 ALOX5 (0.35) ALOX5MEN1CYP2C19KMT2ADRD4
SCHEMBL19389196 0.73 CHRNA7 (0.43) MEN1CYP2C19KMT2AALDH1A1MAOA
SCHEMBL20887127 0.73 PRKDC (0.54) ALOX5MEN1KMT2ADRD4PRKDC
SCHEMBL19976887 0.72 MEN1 (0.35) MEN1CYP2C19KMT2AHSD17B10
SCHEMBL12655471 0.71 PRKDC (0.37) ALOX5MEN1CYP2C19KMT2ADRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-05 US disclosed
US-20230309396-A1 Host Materials for Electroluminscent Devices UNIVERSAL DISPLAY CORPORATION 2023-09-28 US disclosed
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230292606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-11706980-B2 Host materials for electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-18 US disclosed
US-11697662-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-07-11 US disclosed
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-12-09 US disclosed
US-11139443-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-05 US disclosed
US-20200168811-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES UNIVERSAL DISPLAY CORPORATION 2020-05-28 US disclosed
US-8384068-B2 Use of acridine derivatives as matrix materials and/or electron blockers in OLEDs BASF SE (DE) 2013-02-26 US disclosed
US-7989091-B2 Silanes containing phenothiazine-S-oxide or phenothiazine-S,S-dioxide groups and the use thereof in OLEDs BASF SE (DE) 2011-08-02 US disclosed
US-20100219406-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR ELECTRON BLOCKERS IN OLEDS BASF SE (DE) 2010-09-02 US disclosed
US-20100187980-A1 SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS BASF SE (DE) 2010-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11706980-B2 Host materials for electroluminescent devices CRHR1, CRHR2, CRH ALOX5 2940/4885MEN1 1660/4885CYP2C19 1302/4885
US-20230309396-A1 Host Materials for Electroluminscent Devices CRHR1, CRHR2, CRH ALOX5 2710/4885MEN1 1926/4885CYP2C19 1337/4885
US-20100187980-A1 SILANES CONTAINING PHENOTHIAZINE-S-OXIDE OR PHENOTHIAZINE-S,S-DIOXIDE GROUPS AND THE USE THEREOF IN OLEDS OPRD1, PPID, PLOD2 ALOX5 572/4885MEN1 4705/4885CYP2C19 828/4885
US-20200168811-A1 HOST MATERIALS FOR ELECTROLUMINESCENT DEVICES CRHR1, CRHR2, CRH ALOX5 2940/4885MEN1 1660/4885CYP2C19 1302/4885
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 ALOX5 1442/4885MEN1 3516/4885CYP2C19 1590/4885
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP ALOX5 130/4885MEN1 4145/4885CYP2C19 1396/4885
US-11139443-B2 Organic electroluminescent materials and devices ICOSLG, ORC3, OR10J3 ALOX5 3341/4885MEN1 2731/4885CYP2C19 3921/4885
US-20230312628-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIFR, C1R, LBR ALOX5 2070/4885MEN1 1266/4885CYP2C19 2207/4885
US-20210380617-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SOD1, CRKL, ROS1 ALOX5 1259/4885MEN1 2402/4885CYP2C19 3921/4885
US-11697662-B2 Organic electroluminescent materials and devices LIFR, C1R, LBR ALOX5 2342/4885MEN1 977/4885CYP2C19 1964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.