Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3859301 | 0.83 | KMT2A (0.53) | KMT2AMRGPRX4LMNAL3MBTL1MEN1 | |
| SCHEMBL11902604 | 0.83 | CES2 (0.41) | KMT2ACYP1A2PTGDR2NPSR1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3869296 | 0.81 | KMT2A (0.51) | KMT2AMRGPRX4LMNAL3MBTL1MEN1 | |
| SCHEMBL9730220 | 0.80 | PPARG (0.57) | USP30PPARGPPARACYP11B1CYP11B2 | |
| SCHEMBL1714978 | 0.77 | CYP4F2 (0.51) | USP30PPARGPPARACYP11B1CYP11B2 | |
| SCHEMBL18115522 | 0.77 | PPARG (0.50) | USP30PPARGPPARACYP11B1CYP11B2 | |
| SCHEMBL27676369 | 0.75 | KMT2A (0.51) | USP30PPARGPPARACYP11B1CYP11B2 | |
| SCHEMBL28090375 | 0.75 | FAAH (0.46) | PPARGPPARAKMT2AMRGPRX4LMNA | |
| SCHEMBL23706586 | 0.75 | PPARG (0.55) | USP30PPARGPPARACYP11B1CYP11B2 | |
| SCHEMBL10519507 | 0.73 | PPARG (0.47) | USP30PPARGPPARACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202794-A1 | COMPOUNDS | PHARMASSET, INC. (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202794-A1 | COMPOUNDS | HAVCR2, MAVS, GOT2 | USP30 2334/4885PPARG 334/4885PPARA 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.