Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903387 | 0.86 | DHODH (0.36) | TDP1LMNARAB9ASLC6A2SLC6A3 | |
| SCHEMBL11903199 | 0.86 | POLB (0.36) | TDP1ALDH1A1MAPTPOLBLMNA | |
| SCHEMBL11903334 | 0.86 | JAK3 (0.38) | MAPK1ALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL1654718 | 0.84 | TAS1R3 (0.34) | ALDH1A1HSD17B10KDM4EKMT2APKM | |
| SCHEMBL11903222 | 0.82 | SMN1; SMN2 (0.34) | ALDH1A1MAPTSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL11902933 | 0.81 | SMN1; SMN2 (0.34) | TDP1ALDH1A1POLBSMN1; SMN2KDM4E | |
| SCHEMBL11902410 | 0.81 | SMN1; SMN2 (0.34) | TDP1ALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL21584402 | 0.81 | TDP1 (0.39) | TDP1MAPK1ALDH1A1MAPTPOLB | |
| SCHEMBL11902785 | 0.81 | SMN1; SMN2 (0.40) | ALDH1A1MAPTLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL1654720 | 0.80 | KMO (0.41) | ALDH1A1MAPTSMN1; SMN2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | TDP1 2404/4885MAPK1 2973/4885ALDH1A1 718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.