Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903449 | 0.84 | GPR88 (0.48) | GPR88SMN1; SMN2PARP10 | |
| SCHEMBL11903612 | 0.79 | FFAR1 (0.43) | GPR88PARP10MAPT | |
| SCHEMBL15134951 | 0.78 | GPR88 (0.45) | GPR88KMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL15127992 | 0.72 | GPR88 (0.52) | GPR88KMT2AMEN1L3MBTL1FKBP1A | |
| SCHEMBL15054530 | 0.70 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL28344815 | 0.68 | FKBP1A (0.41) | KMT2AMEN1L3MBTL1FKBP1ACARM1 | |
| SCHEMBL28816919 | 0.67 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2L3MBTL1FKBP1A | |
| SCHEMBL10352340 | 0.67 | ALDH1A1 (0.45) | KMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL15375503 | 0.67 | CD274 (0.44) | L3MBTL1PARP10 | |
| SCHEMBL772775 | 0.66 | KMT2A (0.67) | KMT2AMEN1SMN1; SMN2L3MBTL1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486030-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | Bristol-Myers Squibb Company (US) | 2012-08-15 | — | — | EP | disclosed |