Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552902 | 0.72 | L3MBTL1 (0.40) | HCAR2LMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL29020548 | 0.72 | LMNA (0.48) | HCAR2LMNAHSD17B10DAOALDH1A1 | |
| SCHEMBL11903918 | 0.70 | NOTUM (0.41) | HCAR2HSD17B10DAOALDH1A1KDM4E | |
| SCHEMBL8885156 | 0.68 | LMNA (0.36) | HCAR2LMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL29952708 | 0.65 | KDM4E (0.31) | KDM4E | |
| SCHEMBL11860616 | 0.64 | NOTUM (0.61) | HCAR2LMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL9136929 | 0.63 | DAO (0.40) | HCAR2LMNAHSD17B10DAOALDH1A1 | |
| SCHEMBL1009054 | 0.63 | ALDH1A1 (0.39) | HCAR2HSD17B10DAOALDH1A1RXFP1 | |
| SCHEMBL2077234 | 0.63 | HCAR2 (0.52) | HCAR2LMNAHSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL8573447 | 0.63 | ALDH1A1 (0.39) | HCAR2HSD17B10DAOALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487177-A1 | PYRAZOLOXAZOLE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2012-08-15 | — | — | EP | disclosed |