Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544947 | 0.80 | ALDH1A1 (0.50) | L3MBTL1LMNACYP2C19KDM4EKMT2A | |
| SCHEMBL29020548 | 0.75 | LMNA (0.48) | LMNACYP2C19HCAR2FFAR3HSD17B10 | |
| SCHEMBL11733305 | 0.72 | L3MBTL1 (0.63) | L3MBTL1CYP2C19KDM4EHCAR2KMT2A | |
| SCHEMBL11904079 | 0.72 | HCAR2 (0.37) | LMNAKDM4EHCAR2HSD17B10ALDH1A1 | |
| SCHEMBL21328424 | 0.67 | SIRT1 (0.44) | L3MBTL1KDM4EKMT2ATDP1MEN1 | |
| SCHEMBL8885156 | 0.67 | LMNA (0.36) | LMNAKDM4EHCAR2TDP1HSD17B10 | |
| SCHEMBL29948585 | 0.66 | GRIN2D (0.42) | L3MBTL1CYP2C19HCAR2KMT2AMEN1 | |
| SCHEMBL9136929 | 0.66 | DAO (0.40) | L3MBTL1LMNAHCAR2POLBHSD17B10 | |
| SCHEMBL7545210 | 0.66 | HSD17B10 (0.49) | LMNAKDM3BCYP2C19KDM4ETDP1 | |
| SCHEMBL11736480 | 0.66 | KDM4E (0.49) | L3MBTL1KDM4EHCAR2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896043-B1 | Adhesive | TOKUYAMA CORP (JP) | 2002-10-23 | — | — | EP | disclosed |
| EP-0802194-B1 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORP (JP) | 2002-06-19 | — | — | EP | disclosed |
| US-6133338-A | TYPIFIED BY 6-METHACRYLOYLOXYHEXYL 2-THIOURACIL-5-CARBOXYLATE, A RADICAL-POLYMERIZABLE MONOMER, AND A POLYMERIZATION INITIATOR; DENTAL ADHESIVE; GOOD ADHESIVENESS TO NOBLE METALS AND ALLOYS THEREOF | TOKUYAMA CORPORATION (JP) | 2000-10-17 | — | — | US | disclosed |
| EP-0896043-A1 | Adhesive | TOKUYAMA CORPORATION (JP) | 1999-02-10 | — | — | EP | disclosed |
| US-5795497-A | Thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1998-08-18 | — | — | US | disclosed |
| EP-0802194-A2 | Novel thiouracil derivatives and metal surface-treating agent comprising thereof | TOKUYAMA CORPORATION (JP) | 1997-10-22 | — | — | EP | disclosed |