Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 5/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11905203 | 0.89 | MEN1 (0.42) | KDM5AKDM4CALDH1A1TSHRGAA | |
| SCHEMBL11905177 | 0.85 | KDM5A (0.44) | KDM5AKDM4CALDH1A1TSHRPHF8 | |
| SCHEMBL11906028 | 0.85 | KDM5A (0.44) | KDM5AKDM4CALDH1A1TSHRPHF8 | |
| SCHEMBL11905166 | 0.85 | KDM5A (0.48) | KDM5AKDM4CALDH1A1PHF8GAA | |
| SCHEMBL1503265 | 0.84 | LMNA (0.39) | ALDH1A1LMNABCHEACHE | |
| SCHEMBL11906144 | 0.81 | KDM5A (0.30) | KDM5AKDM4C | |
| SCHEMBL11905261 | 0.81 | KDM5A (0.30) | KDM5AKDM4C | |
| SCHEMBL27074659 | 0.80 | LMNA (0.37) | ALDH1A1LMNA | |
| SCHEMBL302546 | 0.80 | LMNA (0.39) | ALDH1A1KDM4ECYP2D6CYP3A4LMNA | |
| SCHEMBL2487913 | 0.79 | MEN1 (0.46) | KDM5AKDM4CTSHRPHF8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567354-B2 | Amino acid-modified silane compounds and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| CN-102702246-B | Amino-acid modified silane compound and preparation method | 信越化学工业株式会社 | 2016-09-28 | — | — | CN | disclosed |
| CN-102702246-A | Amino acid-modified silane compounds and making method | SHINETSU CHEMICAL CO | 2012-10-03 | — | — | CN | disclosed |
| US-20120209020-A1 | AMINO ACID-MODIFIED SILANE COMPOUNDS AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120209020-A1 | AMINO ACID-MODIFIED SILANE COMPOUNDS AND MAKING METHOD | BCAT2, BCAT1, ASNS | KDM5A 804/4885KDM4C 1973/4885ALDH1A1 2045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.