Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.45 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.45 |
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.43 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10256716 | 0.98 | ADRA2A (0.60) | MAPTBLMADRA2AADRA1ACYP1A2 | |
| Hydrochloric Acid SCHEMBL31375742 | 0.87 | MAPT (0.57) | MAPTBLMADRA2AADRA1ACYP1A2 | |
| SCHEMBL13396799 | 0.84 | CYP1A2 (0.57) | MAPTBLMADRA2AADRA1ACYP1A2 | |
| SCHEMBL10716866 | 0.81 | CYP1A2 (0.53) | MAPTBLMADRA2AADRA1ACYP1A2 | |
| SCHEMBL14065210 | 0.80 | ADRA2A (0.68) | MAPTBLMADRA2AADRA1AGAA | |
| SCHEMBL10265711 | 0.80 | CYP1A2 (0.47) | MAPTBLMADRA2AADRA1ACYP1A2 | |
| Succinic Acid Diethyl Ester SCHEMBL29494609 | 0.80 | GAA (0.63) | MAPTBLMADRA2AADRA1ACYP1A2 | |
| Succinic Acid Diethyl Ester SCHEMBL27525301 | 0.80 | GAA (0.63) | MAPTBLMADRA2AADRA1ACYP1A2 | |
| SCHEMBL9630534 | 0.79 | ADRA2A (0.67) | MAPTBLMADRA2AADRA1ACYP1A2 | |
| Bromide SCHEMBL10716902 | 0.79 | CYP1A2 (0.52) | MAPTBLMADRA2AADRA1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450440-B2 | Method for purifying polymer and polymer | MITSUI CHEMICALS, INC. (JP) | 2013-05-28 | — | — | US | disclosed |
| US-20120208976-A1 | METHOD FOR PURIFYING POLYMER AND POLYMER | MITSUI CHEMICALS, INC (JP) | 2012-08-16 | — | — | US | disclosed |