Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10716866 | 0.98 | CYP1A2 (0.53) | CYP1A2ADRA2AADRA1AMAPTBLM | |
| SCHEMBL13396799 | 0.90 | CYP1A2 (0.57) | CYP1A2ADRA2AADRA1AMAPTBLM | |
| SCHEMBL8444876 | 0.89 | CYP1A2 (0.48) | CYP1A2ADRA2AADRA1AMAPTBLM | |
| SCHEMBL9630534 | 0.89 | ADRA2A (0.67) | CYP1A2ADRA2AADRA1AMAPTBLM | |
| Hydrochloric Acid SCHEMBL31375742 | 0.88 | MAPT (0.57) | CYP1A2ADRA2AADRA1AMAPTBLM | |
| Bromide SCHEMBL11571925 | 0.84 | DGKA (0.56) | CYP1A2MAPTALDH1A1TSHRDGKA | |
| Bromide SCHEMBL11327541 | 0.84 | DGKA (0.56) | CYP1A2MAPTALDH1A1TSHRDGKA | |
| Bromide SCHEMBL11326341 | 0.84 | DGKA (0.56) | CYP1A2MAPTALDH1A1TSHRDGKA | |
| SCHEMBL19066941 | 0.83 | CYP1A2 (0.70) | CYP1A2MAPTALDH1A1ALOX15TDP1 | |
| Diethyl Octadecanedioate SCHEMBL496152 | 0.83 | CYP1A2 (0.70) | CYP1A2MAPTALDH1A1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164361-A | Personal care compositions | 高露洁-棕榄公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-0216378-A2 | Haemostatic material and its preparation | Státni vyzkumny ustav textilni (CS) | 1987-04-01 | — | — | EP | disclosed |