Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.50 |
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
| ▸ | SI | P14410 | 1/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13396799 | 0.98 | CYP1A2 (0.57) | MAPTBLMCYP1A2ADRA2AADRA1A | |
| SCHEMBL10716866 | 0.90 | CYP1A2 (0.53) | MAPTBLMCYP1A2ADRA2AADRA1A | |
| SCHEMBL8444876 | 0.89 | CYP1A2 (0.48) | MAPTBLMCYP1A2ADRA2AADRA1A | |
| Bromide SCHEMBL10716902 | 0.88 | CYP1A2 (0.52) | MAPTBLMCYP1A2ADRA2AADRA1A | |
| Hydrochloric Acid SCHEMBL11909677 | 0.87 | MAPT (0.61) | MAPTBLMCYP1A2ADRA2AADRA1A | |
| SCHEMBL10256716 | 0.85 | ADRA2A (0.60) | MAPTBLMCYP1A2ADRA2AADRA1A | |
| SCHEMBL9630534 | 0.84 | ADRA2A (0.67) | MAPTBLMCYP1A2ADRA2AADRA1A | |
| SCHEMBL9302047 | 0.82 | DGKA (0.50) | MAPTBLMCYP1A2ADRA2AADRA1A | |
| SCHEMBL15625159 | 0.82 | BBOX1 (0.57) | MAPTBLMCYP1A2ADRA2AADRA1A | |
| Bromide SCHEMBL1671983 | 0.80 | BBOX1 (0.55) | MAPTBLMCYP1A2ADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250017251-A1 | DIETARY SUPPLEMENT CONTAINING CAYENNE PEPPER POWDER | PERFECT SPORTS INC (CA) | 2025-01-16 | — | — | US | claimed |
| US-20250017251-A1 | DIETARY SUPPLEMENT CONTAINING CAYENNE PEPPER POWDER | PERFECT SPORTS INC (CA) | 2025-01-16 | — | — | US | disclosed |