Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11894515 | 0.82 | HMGCR (0.43) | HMGCR | |
| SCHEMBL2587903 | 0.82 | HMGCR (0.43) | HMGCR | |
| SCHEMBL2585839 | 0.82 | HMGCR (0.43) | HMGCR | |
| SCHEMBL2585837 | 0.82 | HMGCR (0.43) | HMGCR | |
| SCHEMBL1047023 | 0.82 | HMGCR (0.43) | HMGCR | |
| SCHEMBL11895091 | 0.81 | ALDH1A1 (0.38) | HMGCRFAAHALOX5 | |
| SCHEMBL11895089 | 0.81 | ALDH1A1 (0.38) | HMGCRFAAHALOX5 | |
| Potassium Ion SCHEMBL1077457 | 0.80 | FABP3 (0.39) | HMGCRFAAHALOX5 | |
| Potassium SCHEMBL2593640 | 0.74 | KCNH2 (0.42) | HMGCRALOX5 | |
| SCHEMBL11912386 | 0.72 | HMGCR (0.45) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722910-B2 | Diyne compositions | EVOLVA AG (CH) | 2014-05-13 | — | — | US | disclosed |
| US-20120196822-A1 | Diyne Compositions | EVOLVA AG (CH) | 2012-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196822-A1 | Diyne Compositions | OSR1, ERG28, OSBPL3 | HMGCR 2007/4885FAAH 2740/4885CES1 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.