Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | HMGCR | P04035 | 2/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | SELP | P16109 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886617 | 0.87 | KCNH2 (0.50) | KCNH2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5886575 | 0.80 | ADORA3 (0.43) | KCNH2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL1044434 | 0.78 | HMGCR (0.49) | HMGCRPTPN7ALOX5FFAR1FFAR4 | |
| Potassium Ion SCHEMBL1048665 | 0.77 | ALOX5 (0.36) | HMGCRPTPN7ALOX5ALDH1A1CYP3A4 | |
| SCHEMBL1078625 | 0.77 | HPGD (0.37) | HMGCRALOX5ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL11911406 | 0.74 | LIPG (0.41) | ALOX5 | |
| SCHEMBL11911399 | 0.74 | HMGCR (0.39) | HMGCRALOX5 | |
| SCHEMBL13626441 | 0.73 | ALOX5 (0.37) | KCNH2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL15283934 | 0.72 | KCNH2 (0.47) | KCNH2HMGCRPTPN7FFAR1FFAR4 | |
| SCHEMBL5973569 | 0.70 | HMGCR (0.64) | KCNH2HMGCRPTPN7SELP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563769-A1 | DIYNE COMPOSITIONS | EVOLVA AG (CH) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011134538-A1 | DIYNE COMPOSITIONS | EVOLVA LTD (CH) | 2011-11-03 | — | — | WO | disclosed |