SCHEMBL1191256

SCHEMBL1191256

CN(C)C(=O)CCC(=O)N(C)C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.63
CHRNB2 P17787 1/20 0.50
CHRNB4 P30926 1/20 0.50
CHRNA4 P43681 1/20 0.50
PHF8 Q9UPP1 1/20 0.46
KDM2A Q9Y2K7 1/20 0.46
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.39
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
NFKB1 P19838 1/20 0.37
THPO P40225 1/20 0.37
MAPT P10636 1/20 0.37
APEX1 P27695 1/20 0.37
PMP22 Q01453 1/20 0.37
LMNA P02545 1/20 0.36
GAA P10253 2/20 0.34
KDM4A O75164 1/20 0.33
KDM4C Q9H3R0 1/20 0.33
HTT P42858 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL322794 0.87 PHF8 (0.64) ALDH1A1CHRNB2CHRNB4CHRNA4PHF8
SCHEMBL1071900 0.87 ALDH1A1 (0.59) ALDH1A1CHRNB2CHRNB4CHRNA4PHF8
SCHEMBL16816192 0.87 ALDH1A1 (0.52) ALDH1A1CHRNB2CHRNB4CHRNA4PHF8
SCHEMBL10578272 0.87 ALDH1A1 (0.52) ALDH1A1CHRNB2CHRNB4CHRNA4PHF8
SCHEMBL131476 0.86 ALDH1A1 (0.74) ALDH1A1CHRNB2CHRNB4CHRNA4PHF8
SCHEMBL5948495 0.86 ALDH1A1 (0.74) ALDH1A1CHRNB2CHRNB4CHRNA4PHF8
SCHEMBL15412401 0.85 ALDH1A1 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA4PHF8
SCHEMBL2977196 0.85 ALDH1A1 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA4PHF8
SCHEMBL960673 0.85 ALDH1A1 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA4PHF8
Hydrochloric Acid SCHEMBL1375668 0.85 PHF8 (0.61) ALDH1A1CHRNB2CHRNB4CHRNA4PHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9878975-B2 Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides EVONIK DEGUSSA GMBH (DE) 2018-01-30 US claimed
US-7879306-B2 Dispersion and separation of nanostructured carbon in organic solvents ROCHESTER INSTITUTE OF TECHNOLOGY (US) 2011-02-01 US claimed
US-20080008643-A1 Dispersion and separation of nanostructured carbon in organic solvents ROCHESTER INSTITUTE OF TECHNOLOGY (US) 2008-01-10 US claimed
US-5476743-A Thermoplastic resin, a charge director, a liquid component, an additive selected from cyclic carbonates, cyclic sulfones, cyclic sulfoxides and organic amides, pigments, and a charge adjuvant XEROX CORPORATION (US) 1995-12-19 US claimed
US-4960926-A Process for the carbonylation of olefinically unsaturated compounds with a palladium catalyst SHELL OIL COMPANY (US) 1990-10-02 US claimed
US-4481373-A CATALYTIC OXIDATION OF OLEFINS IN PRESENCE OF TERTIARY AMINE OF AMIDE TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1984-11-06 US claimed
US-4039713-A KITCHENWARE COATINGS, FLUOROPOLYMER, ALKALI METAL SILICATE, MICA PARTICLES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-08-02 US claimed
WO-2025005090-A1 COMPOSITE ELECTROLYTE, METHOD FOR PRODUCING SAME, AND POWER STORAGE DEVICE 東亞合成株式会社 2025-01-02 WO disclosed
WO-2024247635-A1 METHOD FOR MANUFACTURING MOLECULAR CRYSTAL AND METHOD FOR MANUFACTURING SOLID ELECTROLYTE 東亞合成株式会社 2024-12-05 WO disclosed
US-10919835-B2 Compounds and synthetic methods for the preparation of retinoid X receptor-specific retinoids Io Therapeutics, Inc. (US) 2021-02-16 US disclosed
US-20200190008-A1 COMPOUNDS AND SYNTHETIC METHODS FOR THE PREPARATION OF RETINOID X RECEPTOR-SPECIFIC RETINOIDS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-06-18 US disclosed
EP-2975620-B1 ALUMINUM ELECTROLYTIC CAPACITOR-USE ELECTROLYTIC SOLUTION AND ALUMINUM ELECTROLYTIC CAPACITOR USING SAME SANYO CHEMICAL IND LTD (JP) 2019-05-22 EP disclosed
US-9878975-B2 Catalytic hydrogenation for producing amines from carboxylic acid amides, carboxylic acid diamides, di-, tri-, or polypeptides, or peptide amides EVONIK DEGUSSA GMBH (DE) 2018-01-30 US disclosed
US-4166168-A POLYMERIZATION PRODUCTS OF ACETYLENE-TERMINATED POLYIMIDE DERIVATIVES PLASTICS ENGINEERING COMPANY (US) 1979-08-28 US disclosed
US-4131730-A Modified polyamic acid from aminophthalic acid anhydride and dianhydride ALELIO GAETANO F D 1978-12-26 US disclosed
US-4118377-A REACTING WITH A CYCLIC DIENE TO FORM ADDUCT, THERMALLY ELIMINATING DIENE TO YIELD EXTENDED BIS-MALEIMIDE UNIVERSITY OF NOTRE DAME DU LAC (US) 1978-10-03 US disclosed
US-4064113-A POLYAMIC ACID ALELIO GAETANO F D 1977-12-20 US disclosed
US-4026904-A Aromatic epoxy-terminated polyimides UNIVERSITY OF NOTRE DAME (US) 1977-05-31 US disclosed
US-3996196-A Polyimide-metallo-phthalocyanines and their preparation UNIVERSITY OF NOTRE DAME DU LAC (US) 1976-12-07 US disclosed
US-3979416-A REFRIGERATED WATER, PRECIPITATION ALELIO GAETANO F D 1976-09-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190008-A1 COMPOUNDS AND SYNTHETIC METHODS FOR THE PREPARATION OF RETINOID X RECEPTOR-SPECIFIC RETINOIDS RXRG, RXRB, RXRA ALDH1A1 835/4885CHRNB2 1342/4885CHRNB4 1527/4885
US-10919835-B2 Compounds and synthetic methods for the preparation of retinoid X receptor-specific retinoids RXRG, RXRB, RXRA ALDH1A1 835/4885CHRNB2 1342/4885CHRNB4 1527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.