Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191256 | 0.87 | ALDH1A1 (0.63) | ALDH1A1LMNACHRNB2CHRNB4CHRNA4 | |
| SCHEMBL16816192 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNACHRNB2CHRNB4CHRNA4 | |
| SCHEMBL19548998 | 0.81 | ALDH1A1 (0.58) | ALDH1A1CHRNB2CHRNB4CHRNA4PHF8 | |
| SCHEMBL28060459 | 0.77 | ALDH1A1 (1.00) | ALDH1A1LMNASLC15A2CHRM1PHF8 | |
| SCHEMBL10001 | 0.77 | — | — | |
| SCHEMBL10578272 | 0.77 | ALDH1A1 (0.52) | ALDH1A1LMNACHRNB2CHRNB4CHRNA4 | |
| SCHEMBL322794 | 0.77 | PHF8 (0.64) | ALDH1A1LMNASLC15A2CHRNB2CHRNB4 | |
| SCHEMBL131476 | 0.75 | ALDH1A1 (0.74) | ALDH1A1LMNACHRNB2CHRNB4CHRNA4 | |
| SCHEMBL5948495 | 0.75 | ALDH1A1 (0.74) | ALDH1A1LMNACHRNB2CHRNB4CHRNA4 | |
| Hydrochloric Acid SCHEMBL1375668 | 0.74 | PHF8 (0.61) | ALDH1A1LMNASLC15A2CHRNB2CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110508253-A | A kind of preparation method of nanofiber adsorbed film | UNIV FUJIAN TECHNOLOGY | 2019-11-29 | — | — | CN | claimed |
| CN-109440228-A | A kind of preparation method of cellulose base carbon nano-fiber | 武汉轻工大学 | 2019-03-08 | — | — | CN | claimed |
| CN-108748627-A | The preparation method of casting concrete beam test specimen temperature control combined steel template | 安徽工业大学 | 2018-11-06 | — | — | CN | claimed |
| CN-108756207-A | The preparation method of casting concrete beam test specimen temperature control Combined plastic formwork | 安徽工业大学 | 2018-11-06 | — | — | CN | claimed |
| US-9060512-B2 | Biocide compositions (III) | COGNIS IP MANAGEMENT GMBH (DE) | 2015-06-23 | — | — | US | claimed |
| US-20120094836-A1 | Biocide Compositions (III) | COGNIS IP MANAGEMENT GMBH (DE) | 2012-04-19 | — | — | US | claimed |
| EP-2269451-A1 | Biocide compositions (III) | Cognis IP Management GmbH (DE) | 2011-01-05 | — | — | EP | claimed |
| WO-2010149301-A2 | BIOCIDE COMPOSITIONS (III) | COGNIS IP MANAGEMENT GMBH (DE) | 2010-12-29 | — | — | WO | claimed |
| US-11718588-B2 | 5-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis | GALAPAGOS NV (BE) | 2023-08-08 | — | — | US | disclosed |
| CN-106977415-B | Intermediate of shakubiqu and preparation method thereof | 广东东阳光药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-110508253-A | A kind of preparation method of nanofiber adsorbed film | UNIV FUJIAN TECHNOLOGY | 2019-11-29 | — | — | CN | disclosed |
| CN-109440228-A | A kind of preparation method of cellulose base carbon nano-fiber | 武汉轻工大学 | 2019-03-08 | — | — | CN | disclosed |
| CN-108748627-A | The preparation method of casting concrete beam test specimen temperature control combined steel template | 安徽工业大学 | 2018-11-06 | — | — | CN | disclosed |
| CN-108756207-A | The preparation method of casting concrete beam test specimen temperature control Combined plastic formwork | 安徽工业大学 | 2018-11-06 | — | — | CN | disclosed |
| EP-0050326-B1 | BENZO(B)THIOPHENES | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-01-29 | — | — | EP | disclosed |
| EP-0155981-A2 | Derivatives of alkoxythiophenol; alkoxyphenolthio carbamates | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-10-02 | — | — | EP | disclosed |
| US-4537976-A | Benzo[b]thiophenes | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-08-27 | — | — | US | disclosed |
| US-4528399-A | Benzo[b]thiophenes intermediates | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-07-09 | — | — | US | disclosed |
| US-4436748-A | HYPOTENSIVES, DIURETICS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1984-03-13 | — | — | US | disclosed |
| EP-0050326-A2 | Benzo(b)thiophenes | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1982-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11718588-B2 | 5-[(piperazin-1-yl)-3-oxo-propyl]-imidazolidine-2,4-dione derivatives as ADAMTS inhibitors for the treatment of osteoarthritis | ADAMTS1, ADAMTS5, ADAMTS7 | ALDH1A1 441/4885LMNA 868/4885SLC15A2 2166/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.