Phosphonic Acid

Phosphonic Acid

SCHEMBL1191383

CC(C)CN(Cl)Cl.O=[PH](O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.41
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41
CYP1A2 P05177 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3380019 0.83
Phosphonic Acid SCHEMBL3380653 0.80 CA12 (0.38) CA12CA1CA2CA9
Phosphonic Acid SCHEMBL1191783 0.71
Phosphonic Acid SCHEMBL1191902 0.71
Phosphonic Acid SCHEMBL9705797 0.67 RNPEP (0.39) MAPK1
Phosphonic Acid SCHEMBL7866708 0.67 RNPEP (0.39) MAPK1
Phosphonic Acid SCHEMBL1199957 0.67
Phosphonic Acid SCHEMBL1199764 0.67 TSHR (0.39) CA1
Phosphonic Acid SCHEMBL3379299 0.67
Isobutane SCHEMBL5096181 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140227201-A1 Antimicrobial Gel Formulations NOVABAY PHARMACEUTICALS, INC. 2014-08-14 US claimed
US-20120282351-A1 System and Method for The Prevention of Bacterial and Fungal Infections Including Urinary Tract Infections (UTI) Using N-Halogenated Amino Acids NOVABAY PHARMACEUTICALS, INC. 2012-11-08 US claimed
US-20110151025-A1 Compositions Comprising N-Halogenated or N,N-Dihalogenated Amine for Treatment and Prophylaxis of Bronchopulmonary Infections NOVABAY PHARMACEUTICALS, INC. 2011-06-23 US claimed
US-20100272783-A1 Methods of Treating Infections of the Nail NOVABAY PHARMACEUTICALS, INC. 2010-10-28 US claimed
US-20100076089-A1 ANTIMICROBIAL GEL FORMULATIONS NOVABAY PHARMACEUTICALS, INC. 2010-03-25 US claimed
US-20100010456-A1 System and Method for the Prevention of Bacterial and Fungal Infections Including Urinary Tract Infection (UTI) Using N-Halogenated Amino Acids NOVACAL PHARMACEUTICALS, INC. 2010-01-14 US claimed
US-20070244449-A1 System and method for the prevention of bacterial and fungal infections including Urinary Tract Infections (UTI) using N-halogenated amino acids NOVACAL PHARMACEUTICALS, INC. 2007-10-18 US claimed
US-20060247209-A1 N-halogenated amino acids, N,N-dihalogenated amino acids and derivatives; compositions and methods of using them NOVABAY PHARMACEUTICALS, INC. 2006-11-02 US claimed
EP-2265267-B1 COMPOSITIONS COMPRISING N-HALOGENATED OR N, N-DIHALOGENATED AMINE FOR TREATMENT AND PROPHYLAXIS OF BRONCHOPULMONARY INFECTIONS GOTTARDI WALDEMAR (AT) 2016-09-21 EP disclosed
US-20140227201-A1 Antimicrobial Gel Formulations NOVABAY PHARMACEUTICALS, INC. 2014-08-14 US disclosed
EP-2725008-A1 N,N-dihalogenated amino acids and derivatives NovaBay Pharmaceuticals, Inc. (US) 2014-04-30 EP disclosed
US-20120282351-A1 System and Method for The Prevention of Bacterial and Fungal Infections Including Urinary Tract Infections (UTI) Using N-Halogenated Amino Acids NOVABAY PHARMACEUTICALS, INC. 2012-11-08 US disclosed
US-20110151025-A1 Compositions Comprising N-Halogenated or N,N-Dihalogenated Amine for Treatment and Prophylaxis of Bronchopulmonary Infections NOVABAY PHARMACEUTICALS, INC. 2011-06-23 US disclosed
US-7893109-B2 N,N-dihalogenated amino acids and derivatives NOVABAY PHARMACEUTICALS, INC. (US) 2011-02-22 US disclosed
US-20100010456-A1 System and Method for the Prevention of Bacterial and Fungal Infections Including Urinary Tract Infection (UTI) Using N-Halogenated Amino Acids NOVACAL PHARMACEUTICALS, INC. 2010-01-14 US disclosed
US-20090023812-A1 N,N-DIHALOGENATED AMINO ACIDS AND DERIVATIVES NOVABAY PHARMACEUTICALS, INC. 2009-01-22 US disclosed
US-7462361-B2 N,N-dihalogenated amino acids and derivatives NOVABAY PHARMACEUTICALS, INC. (US) 2008-12-09 US disclosed
US-20070244449-A1 System and method for the prevention of bacterial and fungal infections including Urinary Tract Infections (UTI) using N-halogenated amino acids NOVACAL PHARMACEUTICALS, INC. 2007-10-18 US disclosed
US-20060247209-A1 N-halogenated amino acids, N,N-dihalogenated amino acids and derivatives; compositions and methods of using them NOVABAY PHARMACEUTICALS, INC. 2006-11-02 US disclosed
US-20050065115-A1 N,N-dihalogenated amino acids and derivatives NOVABAY PHARMACEUTICALS, INC. 2005-03-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090023812-A1 N,N-DIHALOGENATED AMINO ACIDS AND DERIVATIVES DAO, DDC, NRDC CA12 4770/4885CA1 4651/4885CA2 4487/4885
US-20100272783-A1 Methods of Treating Infections of the Nail POLR1C, TYR, NACA CA12 3048/4885CA1 4102/4885CA2 4297/4885
US-20140227201-A1 Antimicrobial Gel Formulations CUTA, TUBA3C, POLR1C CA12 4659/4885CA1 4807/4885CA2 4749/4885
US-20110151025-A1 Compositions Comprising N-Halogenated or N,N-Dihalogenated Amine for Treatment and Prophylaxis of Bronchopulmonary Infections CFTR, NAT1, ELANE CA12 3693/4885CA1 4304/4885CA2 4543/4885
US-20050065115-A1 N,N-dihalogenated amino acids and derivatives DAO, DDC, NRDC CA12 4770/4885CA1 4651/4885CA2 4487/4885
US-20100076089-A1 ANTIMICROBIAL GEL FORMULATIONS CUTA, TUBA3C, POLR1C CA12 4659/4885CA1 4807/4885CA2 4749/4885
US-20060247209-A1 N-halogenated amino acids, N,N-dihalogenated amino acids and derivatives; compositions and methods of using them DAO, ASNS, DDC CA12 4591/4885CA1 3944/4885CA2 3939/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.