Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766001 | 0.83 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR1ADRD2 | |
| SCHEMBL23824909 | 0.83 | HTR1A (0.42) | SLC6A2SLC6A4SLC6A3HTR1ADRD2 | |
| SCHEMBL17070600 | 0.82 | ALDH1A1 (0.53) | SLC6A2SLC6A4SLC6A3IRAK4KCNN4 | |
| SCHEMBL104729 | 0.82 | ALDH1A1 (0.53) | SLC6A2SLC6A4SLC6A3IRAK4KCNN4 | |
| SCHEMBL12528219 | 0.81 | MCHR1 (0.40) | HTR1AHTR7MCHR1IRAK4KCNN4 | |
| SCHEMBL13263183 | 0.81 | KCNN4 (0.41) | HTR1AHTR7MCHR1IRAK4KCNN4 | |
| SCHEMBL16606250 | 0.81 | MCHR1 (0.40) | SLC6A2SLC6A4HTR1AMCHR1IRAK4 | |
| SCHEMBL25835370 | 0.80 | FFAR4 (0.37) | HTR2AMCHR1IRAK4KCNN4ALDH1A1 | |
| SCHEMBL23588427 | 0.80 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3HTR1ADRD2 | |
| SCHEMBL104947 | 0.79 | MCHR1 (0.46) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170014520-A1 | OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF | GENZYME CORPORATION | 2017-01-19 | — | — | US | disclosed |
| US-20120201809-A1 | MULTIFUNCTIONAL ANTIBODY CONJUGATES | COVX TECHNOLOGIES IRELAND, LIMITED (IE) | 2012-08-09 | — | — | US | disclosed |
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170014520-A1 | OLIGOSACCHARIDES COMPRISING AN AMINOOXY GROUP AND CONJUGATES THEREOF | MAN2B1, MAN1B1, GAA | SLC6A2 677/4885SLC6A4 882/4885SLC6A3 602/4885 |
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | SLC6A2 1108/4885SLC6A4 1912/4885SLC6A3 781/4885 |
| US-20120201809-A1 | MULTIFUNCTIONAL ANTIBODY CONJUGATES | CLTB, CLTA, FCGRT | SLC6A2 4516/4885SLC6A4 4815/4885SLC6A3 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.