Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | USP1 | O94782 | 5/20 | 0.37 |
| ▸ | WDR48 | Q8TAF3 | 5/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11918005 | 0.91 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL11918055 | 0.84 | MAPT (0.36) | CYP1A2CYP3A4CYP2C19SMN1; SMN2MAPT | |
| SCHEMBL1654721 | 0.83 | CYP1A2 (0.43) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL11918129 | 0.81 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL1653873 | 0.78 | CYP1A2 (0.42) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL11918042 | 0.78 | — | — | |
| SCHEMBL12786040 | 0.77 | GPR68 (0.45) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL21584410 | 0.77 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 | |
| SCHEMBL11918049 | 0.75 | MEP1B (0.32) | — | |
| SCHEMBL10087278 | 0.75 | USP2 (0.33) | CYP1A2CYP3A4CYP2D6TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (US) | 2012-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202690-A1 | HERBICIDAL COMPOUNDS | DDT, HAO2, HAAO | CYP1A2 75/4885CYP3A4 435/4885CYP2D6 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.