Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR68 | Q15743 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP1 | O94782 | 1/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11918075 | 0.90 | GPR68 (0.44) | GPR68PDE5AMEN1KMT2AGBA1 | |
| SCHEMBL12786042 | 0.82 | ALDH1A1 (0.48) | PDE5AMEN1KMT2AMAPTMAPK1 | |
| SCHEMBL11918064 | 0.82 | GPR68 (0.38) | GPR68PDE5AMEN1KMT2AGBA1 | |
| SCHEMBL11902751 | 0.79 | CYP1A2 (0.44) | GPR68MEN1KMT2ALMNAMAPT | |
| SCHEMBL11918137 | 0.77 | CYP1A2 (0.43) | PDE5AMEN1KMT2ALMNAMAPT | |
| SCHEMBL1653951 | 0.74 | ALDH1A1 (0.43) | GPR68PDE5AMEN1KMT2ALMNA | |
| SCHEMBL11913407 | 0.73 | ALDH1A1 (0.41) | GPR68MEN1KMT2ALMNAMAPT | |
| SCHEMBL11918076 | 0.72 | CYP1A2 (0.41) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL12737648 | 0.72 | HSD17B10 (0.48) | PDE5AMEN1KMT2ALMNAMAPT | |
| SCHEMBL11902674 | 0.70 | ALDH1A1 (0.43) | GPR68MEN1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045561-A2 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2011-04-21 | — | — | WO | disclosed |