SCHEMBL11921753

SCHEMBL11921753

N#COc1ccc(CC(NC(=O)CCCCCOC(=O)c2ccc(N=C=O)cc2)C(=O)OCCCCCC(=O)Oc2ccc(N=C=O)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRSS1 P07477 1/20 0.38
▸ PRSS2 P07478 1/20 0.38
▸ PRSS3 P35030 1/20 0.38
▸ ITGB3 P05106 2/20 0.36
▸ ITGA2B P08514 2/20 0.36
▸ HDAC1 Q13547 10/20 0.36
▸ HDAC6 Q9UBN7 10/20 0.36
▸ MEN1 O00255 1/20 0.35
▸ SLC22A2 O15244 1/20 0.35
▸ TMPRSS2 O15393 1/20 0.35
▸ F2 P00734 1/20 0.35
▸ F10 P00742 1/20 0.35
▸ PLG P00747 1/20 0.35
▸ F12 P00748 1/20 0.35
▸ PLAU P00749 1/20 0.35
▸ PLAT P00750 1/20 0.35
▸ KLKB1 P03952 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ HPN P05981 1/20 0.35
▸ CHRM2 P08172 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11925962 0.94 HDAC1 (0.40) PRSS1PRSS2PRSS3ITGB3ITGA2B
SCHEMBL11921766 0.90 MEN1 (0.35) PRSS1PRSS2PRSS3ITGB3ITGA2B
SCHEMBL15258095 0.87 CYP1A2 (0.35) PRSS1PRSS2PRSS3ITGB3ITGA2B
SCHEMBL16270610 0.86 MEN1 (0.38) PRSS1PRSS2PRSS3ITGB3ITGA2B
SCHEMBL11921762 0.85 PRSS1 (0.34) PRSS1PRSS2PRSS3
SCHEMBL11921747 0.83 PRSS1 (0.37) PRSS1PRSS2PRSS3
SCHEMBL15259407 0.83 CYP1A2 (0.37) PRSS1PRSS2PRSS3ITGB3ITGA2B
SCHEMBL20040326 0.81 MEN1 (0.36) HDAC1MEN1SLC22A2TMPRSS2F2
SCHEMBL11921775 0.81 ITGB3 (0.45) ITGB3ITGA2BHDAC1HDAC6MEN1
SCHEMBL14802443 0.80 PRSS1 (0.37) PRSS1PRSS2PRSS3MEN1SLC22A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2018-07-12 — — US disclosed
US-9868696-B2 Amino acid derivatives and absorbable polymers therefrom Bezwada Biomedial, LLC (US) 2018-01-16 — — US disclosed
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2016-09-08 — — US disclosed
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-06-25 — — US disclosed
US-9012677-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2015-04-21 — — US disclosed
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2015-03-05 — — US disclosed
US-8901341-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-12-02 — — US disclosed
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2013-09-19 — — US disclosed
US-8461372-B2 Amino acid derivatives and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC 2013-06-11 — — US disclosed
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC. (US) 2012-08-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120208896-A1 AMINO ACID DERIVATIVES AND ABSORABLE POLYMERS THEREFROM SLC7A1, SLC3A2, BCAT2 PRSS1 983/4885PRSS2 1002/4885PRSS3 912/4885
US-20150065586-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 PRSS1 878/4885PRSS2 1062/4885PRSS3 966/4885
US-20130245133-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 PRSS1 878/4885PRSS2 1062/4885PRSS3 966/4885
US-20160257643-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 PRSS1 878/4885PRSS2 1062/4885PRSS3 966/4885
US-20150174290-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 PRSS1 878/4885PRSS2 1062/4885PRSS3 966/4885
US-20180194717-A1 AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM SRRM2, SLC7A1, BCAT2 PRSS1 878/4885PRSS2 1062/4885PRSS3 966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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